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Bubbles, ultrasound and radiotherapy: creating a new approach to drug delivery

A team of researchers from the University of Oxford, including Professor Eleanor Stride from the Department’s Institute of Biomedical Engineering, are sharing their respective expertise to unlock exciting new approaches in chemotherapy and radiotherapy using ultrasound.

Microbubbles flourescence microscopy

 Microbubbles used to encapsulate and deliver anti-cancer drugs viewed using fluorescent microscopy. Courtesy of Eleanor Stride.Professor Stride said: ‘We’re extremely fortunate to be working in a building where different types of scientists share the same facilities. Our project came about as the result of a conversation over coffee about using advanced fluorescence microscopy to characterise microbubbles’.


The team will explore how to target chemotherapy drugs by encapsulating them in microbubbles and delivering them through direct injection or via circulation in the bloodstream. To release the drug, while preventing it from affecting nearby healthy tissue, the team will use high-intensity ultrasound waves to burst the bubbles near the tumour.

To read the full story please visit the Cancer Research UK (CRUK) website via this link:

http://www.cancerresearchuk.org/funding-for-researchers/research-features/2016-12-06-bubbles-ultrasound-and-radiotherapy-creating-a-new-approach-to-drug-delivery

For more information about Professor’s Stride research please visit:

http://www.ibme.ox.ac.uk/research/non-invasive-therapy-drug-delivery/people/dr-eleanor-stride