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Publications

Theme 1- Monitoring for Health

Sub-theme 1A – Personalised Perinatal Monitoring

Peer reviewed original research articles

Noble, J.A., Navab, N. and Becher, H.: Ultrasonic image analysis and image-guided interventions. Interface Focus (formerly Journal of the Royal Society Interface), 2011.

M Kuklisova-Murgasova, G Quaghebeur, MA Rutherford, JV Hajnal, JA Schnabel. Reconstruction of fetal brain MRI with intensity matching and complete outlier removal. Medical Image Analysis (2012). In press.

S. Rueda, S. Fathima, C.L. Knight, M. Yaqub, A.T. Papageorghiou, B. Rahmatullah, A. Foi, M. Maggioni, A. Pepe, J. Tohka, R.V. Stebbing, J.E. McManigle, A. Ciurte, X. Bresson, M. Bach Cuadra, C. Sun, G.V. Ponomarev, M.S. Gelfand, M.D. Kazanov, C-W. Wang, H-C. Chen, C-W. Peng, C-M. Hung, and J.A. Noble, “Evaluation and comparison of current fetal ultrasound image segmentation methods for biometric measurements: a grand challenge”. IEEE Transactions on Medical Imaging. In press.

S. Rueda, C. Knight, A.T. Papageorghiou, J.A. Noble, “Fetal arm adipose tissue thickness quantification from ultrasound images: a new tool for fetal nutritional state assessment”. Submitted to Ultrasound in Medicine and Biology.

M Kuklisova-Murgasova, A Cifor, R Napolitano, A Papageorghiou, G Quaghebeur, JA Noble JA Schnabel. “Registration of 3D fetal neurosonography and MRI.” Medical Image Analysis. In press.

Conference proceedings

Rackham, T.M., Rueda, S., Knight, C.L., Noble, J.A.: "Ultrasound image segmentation using feature asymmetry and shape guided live wire", Proceedings of SPIE Medical Imaging 2013: Image Processing, 86690P, February 2013, Orlando, FL, USA.

Rueda, S., Knight, C.L., Papageorghiou, A.T., Noble, J.A.: "Oriented Feature-Based Coupled Ellipse Fitting for Soft Tissue Quantification in Ultrasound Images", IEEE International Symposium on Biomedical Imaging (ISBI) 2013: from Nano to Macro, April 2013, San Francisco, CA, USA.

A. Kopuri, S. Rueda, C. Knight, K. McCormick, A. Noble, A. Papageorghiou, P. Sullivan. 'Neonatal peripheral adiposity measurements using 2D ultasound in premature infants and comparison with fetal adiposity measures- A novel marker for nutritional status'. 48th annual meeting of ESPGHAN, 8-11 May 2013, London UK. 

M Kuklisova-Murgasova, A Cifor, R Napolitano, A Papageorghiou, G Quaghebeur, JA Noble, JA Schnabel. Registration of 3D fetal brain US and MRI. Proc. Medical Imaging and Computer Assisted Interventions (MICCAI), 2-5 October 2012, Nice, France. In press, accepted for oral presentation (3% acceptance rate). 

S. Rueda, C. Knight, A.T. Papageorghiou, J.A. Noble, “Ultrasound-Based Fetal Arm Adipose Tissue Thickness Quantification Across Gestation”, Proceedings of the MICCAI workshop on Perinatal and Paediatric Imaging: PaPI 2012, 1st October 2012, Nice, France. 

A. Ciurte, S. Rueda, X. Bresson, S. Nedevschi, A.T. Papageorghiou, J.A. Noble, M. Bach Cuadra, “Ultrasound Image Segmentation of the Fetal Abdomen: a Semi-Supervised Patch-Based Approach”, Proceedings of the MICCAI workshop on Perinatal and Paediatric Imaging: PaPI 2012, 1st October 2012, Nice, France. 

S. Rueda, C. Knight, A.T. Papageorghiou, J.A. Noble, “Novel automatic method for measuring fetal arm adipose tissue in 2D ultrasound images across gestation”, Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2012, 9-12 September 2012, Copenhagen, Denmark.

M. Ahmed, S. Rueda, C. Knight, A.T. Papageorghiou, J.A. Noble, “Assessing fetal fractional arm adipose tissue volume using 3D ultrasound: the importance of measuring perpendicular to the humerus”, Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2012, 9-12 September 2012, Copenhagen, Denmark.

C. Knight, S. Rueda, J.A. Noble, A.T. Papageorghiou, “Fetal arm fat: development throughout pregnancy in selectively screened optimally healthy patients”, Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2012, 9-12 September 2012, Copenhagen, Denmark.

C. Knight, S. Rueda, J.A. Noble, A.T. Papageorghiou, “Fetal arm fat: an in utero marker of body composition?”, Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2012, 9-12 September 2012, Copenhagen, Denmark. 

S. Rueda, C. Knight, A.T. Papageorghiou, J.A. Noble, “Regularised Feature-Based Fuzzy Connectedness Segmentation of Ultrasound Images for Fetal Soft Tissue Quantification Across Gestation”, IEEE International Symposium on Biomedical Imaging (ISBI) 2012: from Nano to Macro, pp. 1323-1326, 2nd-5th May 2012, Barcelona, Spain

S Wang, M Kuklisova-Murgasova, JA Schnabel. An atlas-based method for neonatal MR brain tissue segmentation. MICCAI Grand Challenge: Neonatal Brain Segmentation, 5 October 2012, Nice, France.

M Murgasova, G Quaghebeur, JV Hajnal, JA Schnabel. Unified framework for superresolution reconstruction of 3D fetal brain MR images from 2D slices with intensity correction and outlier rejection. MICCAI Workshop on Image Analysis of Human Brain Development, Toronto, Canada, 2011.

Z Wu, M Murgasova, A Buchmann, M von Rhein, JA Schnabel. Brain Extraction Methods for Neonates. Medical Image Understanding and Analysis (MIUA), 13-15th July 2011, London, UK.

B Rahmatullah, I Sarris, C Ioannou, CL Knight, JA Noble, AT Papageorghiou. Automated fetal biometry image landmark detection for confirming correct image planes: abdominal circumference. Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology 2012 (ISUOG), 9-12 September 2012, Copenhagen, Denmark.

R Napolitano, M Yaqub, C Ioannou, CL Knight, JA Noble, AT Papageorghiou. Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology 2012 (ISUOG), 9-12 September 2012, Copenhagen, Denmark.

Kuklisova-Murgasova, M., Quaghebeur, G., Hajnal, J.V., Noble, J.A., Schnabel, J.A.: Towards registration of fetal brain MR and ultrasound. 9th IEEE International Symposium on Biomedical Imaging (ISBI) 2012, Page(s): 346 - 349.

Noble, J.A.: "Image analysis of the human fetus and newborn - developing new clinical tools for perinatal care", Special Session on Fetal and Neonatal Imaging, Proceedings of the International Symposium on Biomedical Imaging (ISBI), pp. 490-492, 2-5 May 2012, Barcelona, Spain.

Image analysis of the human fetus and newborn - developing new clinical tools for perinatal care, accepted to IEEE ISBI 2012 (invited talk)

Kuklisova-Murgasova, M., Quaghebeur, G., Schnabel, J.A.: 3D Reconstruction of fetal brain MRI, Proc. ASNR 50th Annual Meeting, 23rd - 26th April 2012, New York, USA.

Murgasova, M., Quaghebeur, G., Hajnal, J., Schnabel, J.A.: Unified framework for superresolution reconstruction of 3D fetal brain MR images from 2D slices with intensity correction and outlier rejection, Proc. MICCAI Workshop on Image Analysis of Human Brain Development (IAHBD), 2011

Fathima, S., Rueda, S., Papageorghiou, A. and Noble, J.A.: A novel local-phase method of automatic atlas construction in fetal ultrasound. Proc. SPIE Medical Imaging 2011: Image Processing, Volume 7962, 79621A, 14th February 2011, Orlando, FL, USA

Rueda, S., Knight, C., Papageorghiou, A. and Noble, J.A.: Local phase-based fuzzy connectedness segmentation of ultrasound images. Proc. Medical Image Understanding and Analysis (MIUA), 14th-15th July 2011, London, UK

Wu, Z., Murgasova, M., Buchmann, A., von Rhein, M. and Schnabel, J.A.: Brain extraction methods for neonates. Proc. Medical Image Analysis and Understanding (MIUA), 14th-15th July 2011, London, UK

Meeting Abstracts

M Kuklisova-Murgasova, G Quaghebeur, JA Schnabel. 3D Reconstruction of fetal brain MRI. Proc. ASNR 50th Annual Meeting, New York, April 23-26, 2012.

A. Kopuri, S. Rueda, C. Knight, K. McCormick, A. Noble, A. Papageorghiou, P. Sullivan. 'Neonatal peripheral adiposity measurements using 2D ultasound in premature infants and comparison with fetal adiposity measures- A novel marker for nutritional status'. 48th annual meeting of ESPGHAN, 8-11 May 2013, London UK. 

S. Rueda, “Perinatal Adiposity Score: A New Biomarker for Personalised Perinatal Monitoring?”, Proc. Symposium on Medical Imaging Meets Computer Vision, The Rank Prize Funds, Grasmere, U.K., 18-21 March 2013. 

C.L. Knight, S. Rueda, M. Ahmed, J.A. Noble, A.T. Papageorghiou, Fetal arm ultrasound as a marker of fetal body composition, Blair Bell Meeting 2012.

Rueda, S., Knight, C., Papageorghiou, A.T., Noble, J.A.: “Novel automatic method for measuring fetal arm adipose tissue in 2D ultrasound images across gestation”, Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2012, 9-12 September 2012, Copenhagen, Denmark.

Ahmed, M., Rueda, S., Knight, C., Papageorghiou, A.T., Noble, J.A.: “Assessing fetal fractional arm adipose tissue volume using 3D ultrasound: the importance of measuring perpendicular to the humerus”, Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2012, 9-12 September 2012, Copenhagen, Denmark.

Knight, C., Rueda, S., Noble, J.A., Papageorghiou, A.T.: “Fetal arm fat: development throughout pregnancy in selectively screened optimally healthy patients”, Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2012, 9-12 September 2012, Copenhagen, Denmark.

Knight, C., Rueda, S., Noble, J.A., Papageorghiou, A.T.: “Fetal arm fat: an in utero marker of body composition?”, Proceedings of the 22nd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2012, 9-12 September 2012, Copenhagen, Denmark.

S Rueda, CL Knight, AT Papageorghiou, JA Noble. Systematic thickness analysis of the adipose tissue around the fetal arm across gestation using 2D ultrasound images. Proceedings of the 23rd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2013, 6-9 October 2013, Sydney, Australia.

S Rueda, CL Knight, AT Papageorghiou, JA Noble. Novel automatic coupled ellipse fitting tool for fetal arm adipose tissue quantification in 2D ultrasound images across gestation. Proceedings of the 23rd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2013, 6-9 October 2013, Sydney, Australia.

CL Knight, S Rueda, JA Noble, AT Papageorghiou. Fetal fat index: a novel technique to assess fetal arm fat. Proceedings of the 23rd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2013, 6-9 October 2013, Sydney, Australia.

CL Knight, S Rueda, M Ahmed, K Edwards, JA Noble, AT Papageorghiou. Fetal arm volumetry: a novel assessment of fetal body composition in the second and third trimester. Proceedings of the 23rd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2013, 6-9 October 2013, Sydney, Australia.

M Ahmed, CL Knight, S Rueda, AT Papageorghiou, JA Noble. Assessing fetal fractional arm volume using varying numbers of cross-sectional slices. Proceedings of the 23rd World Congress on Ultrasound in Obstetrics and Gynecology - ISUOG 2013, 6-9 October 2013, Sydney, Australia.

Books

Rueckert, D., and Schnabel, J.A.: Medical Image Registration. Deserno, T.M.  Ed., Biomedical Image Processing Series on Biological and Medical Physics, Biomedical Engineering, Springer, 2011

Sub-theme 1B - Telehealth for the developing world

Meeting Abstracts

T. Brennan, G. Clifford and L. Tarassenko. Integrating low-cost sensors with mobile phones for remote monitoring of long-term conditions in resource constrained environments; International Bioelectronics Workshop, Sydney 2011

T. Brennan. SMS-text Adherence Reminder (StAR) Study: Delivering and Evaluating mHealth Solutions in resource-constrained environments; mHealth Africa Summit, Johannesburg 2012

Sub-theme 1C – Telemedicine in the developed world: vital sign monitoring in the home

Peer reviewed original research articles

Pimentel, M.A.F., Clifton, D.A., Clifton, L., Watkinson, P.J., and Tarassenko, L.: Modelling Physiological Deterioration in Post-operative Patient Vital-Sign Data. Medical & Biological Engineering & Computing.

Clifton, L., Clifton, D.A., Pimentel, M.A.F., Watkinson, P.J., and Tarassenko, L.: Gaussian Processes for Personalised e-Health Monitoring with Wearable Sensors, IEEE Transactions on Biomedical Engineering. Accepted for publication.

Clifford, G.D. and Clifton, D.A.: Annual Review: Wireless Technology in Disease State Management and Medicine, Annual Review of Medicine 63, 2012, pp. 479-492.

Pimentel, M.A.F., Clifton, D.A., Clifton, L., and Tarassenko, L.: Novelty Detection and Anomaly Detection, Submitted to: IEEE Selected Topics in Signal Processing.

Clifton, L., Clifton, D.A., Zhang, Y., Watkinson, P., Tarassenko, L., and Yin, H: Probabilistic Novelty Detection with Support Vector Machines. Submitted to: IEEE Transactions on Reliability.

Clifton, D.A., Wong, D., Clifton, L. Pullinger, R., and Tarassenko, L.: Patient Monitoring with Machine Learning in the Emergency Department – A Large-Scale Clinical Study. Submitted to: IEEE Transactions on Information Technology in Biomedicine.

Clifton, L., Clifton, D.A., Pimentel, M.A.F., Watkinson, P.J., and Tarassenko, L.: A Machine Learning Approach to e-Health using Wearable Patient Monitors. Submitted to: Annals of Biomedical Engineering. 

Meredith, D., Clifton, D.A., Charlton, P., Brooks, J., Pugh, C.W., and Tarassenko, L.:Photoplethysmographic Derivation of Respiratory Rate: A Review of Relevant Respiratory and Circulatory Physiology, Journal of Medical Engineering and Technology 36(1), 2012, pp. 60 - 66.

Tarassenko, L. and Clifton, D.A.: Semiconductor Wireless Technology for Chronic Disease Management, Electronics Letters S30, 2011, pp. 30-32 (Invited article)

Tarassenko, L., Clifton, D.A., Pinsky, M.R., Hravnak, M.T., Woods, J.R., and Watkinson, P.: Centile-Based Early Warning Scores Derived from Statistical Distributions of Vital Signs.Resuscitation 82 (8), 2011, pp. 1013-1018

Hugueny, S., Clifton, D.A., and Tarassenko, L.: Probabilistic Patient Monitoring with Multivariate, Multimodal Extreme Value Theory, Biomedical Engineering Systems and Technologies, Communications in Computer Science 127, 2011, pp. 199-211. (Invited article, from IEEE Biomedical Engineering Systems and Technologies)

Clifton, D.A., Hugueny, S., and Tarassenko, L.: Novelty Detection with Multivariate Extreme Value Statistics. Journal of Signal Processing Systems 65, 2011, pp.371-389 

Clifton, D.A., Clifton, L.A., Alvi, M., Khalid, S., Meredith, D., Price, J., Watkinson, P., and Tarassenko, L.: Towards Assisted Living via Probabilistic Vital-Sign Monitoring in the Home. IET Assisted Living, London, UK, 2011, pp. 9-14

Khalid, S., Clifton, D.A., Clifton, L.A., and Tarassenko, L: Optimising Classifiers for the Detection of Physiological Deterioration in Patient Vital-Sign Data. IEEE Biomedical Engineering Systems and Technologies, Rome, Italy, 2011.

Hugueny, S., Clifton, D.A., and Tarassenko, L.: Probabilistic Patient Monitoring with Multivariate, Multimodal Extreme Value Theory Biomedical Engineering Systems and Technologies, Communications in Computer Science 127, 2011, pp. 199-211. (Invited article, from IEEE Biomedical Engineering Systems and Technologies)

Chykeyuk, K., Clifton, D.A., and Noble, J.A.: Feature Extraction and Wall Motion Classification of 2-D Stress Echocardiography with Relevance Vector Machines.  IEEE Biomedical Imaging, 2011. 

Chykeyuk, K., Clifton, D.A., and Noble, J.A.: Support Vector Machines for Wall Motion Classification of 2-D Stress Echocardiography. SPIE Medical Imaging, 2011. 

Clifton, D.A., Clifton, L.A., Alvi, M., Khalid, S., Meredith, D., Price, J., Watkinson, P., and Tarassenko, L.: Towards Assisted Living via Probabilistic Vital-Sign Monitoring in the Home. IET Assisted Living, 2011. 

Clifton, D.A., Wong, D., Fleming, S., Way, R., Wilson, S., Pullinger, R., and Tarassenko, L.: Identifying Patient Deterioration in the Emergency Department using Data Fusion Systems.  British Medical Journal Quality and Safety in Healthcare, 2011.  

Wilson, S., Wong, D., Clifton, D.A., Fleming, S., Way, R., Pullinger, R., and Tarassenko, L.: An Evaluation of the Use of Track and Trigger in the Emergency Department. Emergency Medical Journal, 2011. 

Clifford, G.D. and Clifton, D.A.: Annual Review: Wireless Technology in Disease State Management and Medicine. Annual Review of Medicine (invited article), 2011. 

Clifton, L.A., Clifton, D.A., Zhang, Y., Watkinson, P., Tarassenko, L., and Yin, H:  Novelty Detection with Support Vector Machines. IEEE Transactions on Systems, Man, and Cybernetics (Part B), 2011.

Clifton, L.A., Clifton, D.A., Watkinson, P.J., and Tarassenko, L.: Identification of Patient Deterioration in Vital-Sign Data using One-Class Support Vector Machines. IEEE Artificial Intelligence in Medical Applications, Poland, 2011. 

Clifton, D.A., Hugueny, S., and Tarassenko, L.: Pinning the Tail on the Distribution: A Multivariate Extension to the Generalised Pareto Distribution. IEEE Machine Learning and Signal Processing, Beijing, China, 2011. 

Khalid, S., Clifton, D.A., Clifton, L.A., and Tarassenko, L.: A Two-Class Approach to the Detection of Physiological Deterioration in Patient Vital Signs, with Clinical Label Refinement. IEEE Transactions on Information Technology in Biomedicine, 2011. 

Borhani, Y., Fleming, S., Clifton, D.A., Sutherland, S., Hills, L., Meredith, D., Pugh, C., and Tarassenko, L.: Towards a Data Fusion Model for Predicting Deterioration in Dialysis Patients. Computers in Cardiology, Belfast, UK, 2010. 

Clifton, D.A., Meredith, D., Borhani, Y., Price, J., Pugh, C., and Tarassenko, L.: Probabilistic Early Warning Systems for Detecting Patient Deterioration in the Home. IEEE Advances in Digital Healthcare: Telehealth and Mobile Health, 2010

Hugueny, S., Clifton, D.A., and Tarassenko, L.: Understanding Vital-Sign Abnormalities in Critical Care Patients. Critical Care 14(1), 2010

Mohseni, J., Kringelbach, M., Probert Smith, P., Stein, J., and Aziz, T.: Application of Null-Beamformer to Source Localization of MEG Data in Deep Brain Stimulation, Proc IEEE EMBC Conference, Buenos Aires, Argentina, September 2010.

Sutherland, S., Hills, L., Meredith, D., Borhani, Y., Clifton, D.A., Fleming, S., Mosson, A, Thornley,A., Tarassenko, L. and Pugh, C.: Integrated Vital Sign Monitoring of Haemodyalisis Patients: Pilot Study. 39th European Renal Care Association Conference, Dublin, Ireland, 2010.

Hugueny, S., Clifton, D.A., and Tarassenko, L: Probabilistic Patient Monitoring Using Extreme Value Theory. IEEE Biomedical Engineering Systems and Technologies, Valencia, Spain, 2010, pp. 5-12. (Abbey-Santander prize, BIOSTEC Best Overall Paper prize)

Clifton, D.A., Hugueny, S., and Tarassenko, L.: A Comparison of Approaches to Multivariate Extreme Value Theory for Novelty Detection. IEEE Statistical Signal Processing, Cardiff, UK, 2009, pp. 13-16

Clifton, D.A., Hugueny, S., and Tarassenko, L.: Novelty Detection with Multivariate Extreme Value Theory, Part I: A Numerical Approach to Multimodal Estimation. IEEE Machine Learning in Signal Processing, Grenoble, France 2009, pp. 1-6

Hugueny, S., Clifton, D.A., and Tarassenko, L: Novelty Detection with Multivariate Extreme Value Theory, Part II: An Analytical Approach to Unimodal Estimation. IEEE Machine Learning in Signal Processing, Grenoble, France 2009, pp. 1-6

Tarassenko, L., Clifton, D.A., Bannister, P.R., King, S., and King, D.: Novelty Detection. Worden, K., et al. (eds): Encyclopaedia of Structural Health Monitoring, Wiley, 2009.

Tarassenko, L. and Clifton, D.A.: Semiconductor Wireless Technology for Chronic Disease Management Electronics Letters S30, 2011, pp. 30-32 

Conference Proceedings

Clifton, D.A., Hugueny, S., Clifton, L., Wong, D., and Tarassenko, L.: Novelty Detection with Extreme Function Theory, Neural Information Processing Systems (NIPS), Lake Tahoe, USA, 2012 [in review]

Wong, D., Clifton, D.A., and Tarassenko, L.: Probabilistic Detection of Vital Sign Abnormality with Gaussian Process Regression, IEEE 12th Int. Conf. Bioinformatics and Bioengineering (BIBE), Cyprus, 2012 [in press]

Clifton, L.A., Clifton, D.A., Pimento, M.A.F., Watkinson, P.J., and Tarassenko, L.: Gaussian Process Regression in Vital-Sign Early Warning Systems, IEEE Engineering in Medicine and Biology Conference, San Diego, USA, 2012 [in press]

Clifton, D.A., Gibbons, J., Davies, J., and Tarassenko, L.: Machine Learning and Software Engineering in Health Informatics, IEEE 34th International Conference on Software Engineering, Zurich, Switzerland, 2012, pp.37 – 41.

Tarassenko, L., Clifton, D.A., Gibson, O., Villaroel, M., Watkinson, P., and Farmer, A.: Wireless Health: From Technology to Integration within the UK Health System, Wireless Health, San Diego, USA, 2012 [in press].

Pimentel, M.A.F., Clifton, D.A., Clifton, L.A., Watkinson, P.J., and Tarassenko, L.: Vital-Sign Data Fusion Models for Post-operative Patients  IEEE EMBS Biomedical Engineering Systems and Technologies, Algarve, Portugal, 2012, pp. 410 – 413.

Clifton, D.A., Hugueny, S., and Tarassenko, L.: Pinning the Tail on the Distribution: A Multivariate Extension to the Generalised Pareto Distribution, IEEE Machine Learning and Signal Processing, Beijing, China, 2011, pp. 1-6.

Clifton, L.A., Clifton, D.A., Watkinson, P.J., and Tarassenko, L.: Identification of Patient Deterioration in Vital-Sign Data using One-Class Support Vector Machines, IEEE SMC Artificial Intelligence in Medical Applications, Poland, 2011, pp. 125 - 131.

Clifton, D.A., Wong, D., Fleming, S., Wilson, S., Way, R., Pullinger, R., and Tarassenko, L.: Novelty Detection for Identifying Deterioration in Emergency Department Patients, 12th Int. Conf. on Intelligent Data Engineering and Automated Learning, Norwich, UK, 2011, in Yin, H., Wang, W., and Rayward-Smith, V. (eds): Lecture Notes in Computer Science 6936, Springer-Verlag, Heidelberg, 2011, pp. 220-227

Clifton, D.A., Wong, D., Fleming, S., Way, R., Wilson, S., Pullinger, R., and Tarassenko, L.: Identifying Patient Deterioration in the Emergency Department using Data Fusion Systems.Proc. British Medical Journal International Conference of Quality and Safety in Healthcare, 5th-8th April 2011, Amsterdam, Netherlands. 

Khalid, S., Clifton, D.A., Clifton, L.A., and Tarassenko, L: Optimising Classifiers for the Detection of Physiological Deterioration in Patient Vital-Sign Data. Proc. IEEE Biomedical Engineering Systems and Technologies, 26th-29th January 2011, Rome, Italy. 

Clifton, D.A., Wong, D., Fleming, S., Wilson, S., Way, R., Pullinger, R., and Tarassenko, L.: Novelty Detection for Identifying Deterioration in Emergency Department Patients. Proc. 12th Int. Conf. on Intelligent Data Engineering and Automated Learning, 7th-9th September 2011 Norwich, UK, 2011. 

Meeting Abstracts

Clifton, D.A., Hugueny, S., and Tarassenko, L.: Novelty Detection and Extreme Value Analysis. IEEE Computational Intelligence and Learning Benelux, 2010

Clifton, D.A. and Tarassenko, L.: Machine Learning Techniques for Early Warning of Patient Deterioration. Wellcome Trust Conference on Predictive Modelling using Medical Data, Dundee, 2010

Meredith, D., Borhani, Y., Sutherland, S., Hills, L., Fleming, S., Clifton, D.A., Thornley, A., Tarassenko, L., and Pugh, C.: Monitoring of Vital Signs During Haemodyalisis. British Renal Association Conference, Manchester, UK, 2010, p.355

Orphanidou, C., Clifton, D.A., Smith, M., Feldmar, J., and Tarassenko, L.: Telemetry-Based Vital-Sign Monitoring for Ambulatory Hospital Patients. IEEE Engineering in Medicine and Biology, Minneapolis, USA, pp. 4650-4653.

Sundaram, S., Clifton, D.A., and McDonald, K.: Stable Distributions for Heavy-Tailed Data and their Application in Asset Health Monitoring. IET Condition Monitoring, Stratford, UK, 2010.

Clifton, D.A., Clifton, L.A., and Tarassenko, L.: Patient-Specific Biomedical Condition Monitoringfor Post-operative Cancer Patients. IET Condition Monitoring, Dublin, Ireland, 2009, pp. 424-433.

Wong, D., Clifton, D.A., and Tarassenko, L.: An introduction to the Bispectrum for EEG Analysis. IEEE PGBIOMED, Oxford, UK, 2009.

Books

Tarassenko, L., Clifton, D.A., Bannister, P.R., King, S., and King, D.: Novelty Detection. Worden, K., et al. Ed., Encyclopaedia of Structural Health Monitoring, Wiley, 2009

Sub-theme 1D – Neurodegenerative diseases (Deep-Brain Stimulation)

Peer-Reviewed Original Research Articles
 
J.-S. Brittain, P. Probert-Smith, T. Z. Aziz and P. Brown. Tremor suppression by rhythmic transcranial current stimulation. Current Biology, 23 (5): 436-440, Mar 2013.
 
Hamid R. Mohseni , Penny P. Smith, Christine E. Parsons , Katherine S. Young , Jonathan A. Hyam, Alan Stein, John F. Stein, Alexander L. Green, Tipu Z. Aziz, Morten L. Kringelbach  (2012) MEG Can Map Short and Long-Term Changes in Brain Activity following Deep Brain Stimulation for Chronic Pain. PLoS ONE 7(6): e37993.
 
Mohseni, H.R.; Woolrich, M.W.; Kringelbach, M.L.; Luckhoo, H.; Smith, P.P.; Aziz, T.Z.; , "Fusion of Magnetometer and Gradiometer Sensors of MEG in the Presence of Multiplicative Error," IEEE Transactions on Biomedical Engineering, vol.59, no.7, pp.1951-1961, July 2012.
 
J.-S. Brittain, K. Watkins, R. A. Joundi, N. Ray, P. Holland, A. L. Green, T. Z. Aziz and N. Jenkinson. A role for the subthalamic nucleus in response inhibition during conflict. Journal of Neuroscience. Accepted for publication. 
 
R. A. Joundi, V. Lopez-Alonso, A. Lago, J.-S. Brittain, M. Fernandez-del-Olmo, P. Gomez-Garre, P. Mir, Ned Jenkinson, B. Cheeran and P. Brown. The effect of BDNF val66met polymorphism on visuomotor adaptation. Experimental Brain Research, Accepted.
 
R. A. Joundi, J.-S. Brittain, A. L. Green, T. Z. Aziz, P. Brown and N. Jenkinson. Persistent suppression of subthalamic beta-band activity during rhythmic finger tapping in Parkinson's disease. Clinical Neurophysiology, Accepted.
 
R. A. Joundi, J.-S. Brittain, A. L. Green, T. Z. Aziz and N. Jenkinson. High-frequency stimulation of the subthalamic nucleus selectively decreases central variance of rhythmic finger tapping in Parkinson's disease. Neuropsychologia, In Press.
 
R. A. Joundi, J.-S. Brittain, A. L. Green, T. Z. Aziz, P. Brown and N. Jenkinson. Oscillatory activity at in the subthalamic nucleus during arm reaching in Parkinson's disease. Experimental Neurology, 236(2): 319-326, Aug 2012. 
 
R. A. Joundi, J.-S. Brittain, D. T. Punt, A. L. Green, N. Jenkinson and T. Z. Aziz. Stimulation of the subthalamic nucleus improves velocity of ballistic movements in Parkinson's disease. NeuroReport, 23(6): 390-4, Apr 2012. 
 
R. A. Joundi, N. Jenkinson, J.-S. Brittain, T. Z. Aziz and P. Brown. Driving oscillatory activity in the human cortex enhances motor performance. Current Biology, 22(5): 403-7, Feb 2012.
 
N. J. Ray, J.-S. Brittain, P. Holland, R. A. Joundi, J. F. Stein, T. Z. Aziz and N. Jenkinson. The role of the subthalamic nucleus in response inhibition: Evidence from Local Field Potential recordings in the human Subthalamic nucleus. NeuroImage, 60(1): 271-8, Mar 2012.
 
N. Jenkinson, J.-S. Brittain, S. L. Hicks, C. Kennard and T. Z. Aziz. On The Origins of Oscillopsia. Stereotactic and Functional Neurosurgery, 90(2): 124-9, Apr 2012.
 
Conference proceedings
 
Hamid Mohseni: ‘Using DBS-MEG to understand chronic pain’ 18th International Conference on Biomagnetism, Aug 2012
 
Brittain, J.-S. and Halliday, D.M.: Optimal spectral tracking-Adapting to dynamic regime change. Journal of Neuroscience Methods 195 (1), pp. 111-115, 2011.
 
Brittain, J.S, Probert Smith, P., and Aziz,T.: Demand Driven Deep Brain Stimulation: Regimes and Autoregressive Hidden Markov implementation, Proc IEEE EMBC Conference, Buenos Aires, Argentina, September 2010.
 
Mohseni, J., Kringelbach, M., Probert Smith, P., Stein J., and Aziz, T.: Application of Null-Beamformer to Source Localization of MEG Data in Deep Brain Stimulation, Proc IEEE EMBC Conference, Buenos Aires, Argentina, September 2010.
 
Meeting Abstracts
 
J.S. Brittain. Driving oscillatory activity in the human cortex modulates motor behaviour. BACN symposium, Newcastle, April 2012
 
M. Kringelbach. MEG imaging of pain patients. Society for Neuroscience (SFN) 2011, Washington DC
 
H. Mohseni. An overview of Bayesian filtering and its applications to neuronal data’. Seminar Group, MRC CBU, Cambridge
 
Mohseni, J., Kringelbach, M., Woolrich, M.W. ,Probert Smith, P., and Aziz, T.: A fast solution to a minimum beam variance beamformer and its application to simultaneous MEG and local field potentials signals. IEEE ICASSP conference, Prague, May 2011
 
Mohseni, J., Kringelbach, M., and Probert Smith, P.: Analysis of the Magnetoencephalogram (MEG) and Local Field Potential (LFP) of Patient Suffering from Chronic Pain (Poster). Interacting with Brain Oscillations Workshop, UCL, June 2010.
 

Theme 2 – Monitoring drug discovery for cancer

Peer-reviewed original research articles
 
S. Mo, C.-C. Coussios, L. Seymour and R. Carlisle, “Ultrasound-enhanced drug delivery for cancer”, Expert Opinion on  Drug Delivery – in press.
 
C.M. Coviello, R.J. Kozick, A. Hurrell, P. Probert-Smith and C.-C. Coussios, “Thin-Film, Sparse Boundary Array Design for Passive Acoustic Mapping during Ultrasound Therapy”, IEEE Trans. UFFC (2012) – in press.
 
R. Carlisle, L. Seymour and C.-C. Coussios, ‘Targeting of Liposomes via PSGL1 for Enhanced Tumor Accumulation’, Pharmaceutical Research (2012) – in press.
 
R Laga, R Carlisle, M. Tangney , K. Ulbrich, LW Seymour, “Polymer Coatings for Delivery of Nucleic Acid Therapeutics”, J Control Release. 61(2):537-53 (2012)
 
M. Bazan-Perergrino, B. Rifai, R. Carlisle, J. Choi, C. Arvanitis, L. Seymour and C-C. Coussios, ‘Cavitation-Enhanced Delivery of a Conditionally Replicating Oncolytic Adenovirus by Therapeutic Ultrasound’, Cancer Research (2012) – in press. 
 
A Cifor, L. Risser, D. Chung, E.M. Anderson, J.A. Schnabel, “Hybrid Feature-Based Diffeomorphic Registration for Tumour Tracking in 2-D Liver Ultrasound Images”. Submitted to  IEEE Transactions on Medical Imaging, 2012.
 
A. Larrue, A. Noble, Modelling of errors in Nakagami Imaging : illustration on breast masses characterization. Submitted to Ultrasound in Medicine and Biology
 
Arora, M., Arvanitis, C. and Coussios, C-.C.: Microparticle-Based Cavitation Nucleation for Enhancement of Ultrasound Therapy. Ultrasonics, 2011. 
 
Gyongy, M. and Coviello, C.M.: Passive cavitation mapping with temporal sparsity constraint. Journal of the Acoustical Society of America, 2011. 
 
Bazan-Perergrino, M., Rifai, B., Carlisle, R.C., Choi, J., Arvanitis, C., Seymour, L.W. and Coussios, C-C.: Cavitation-Enhanced Delivery of a Conditionally Replicating Oncolytic Adenovirus to Tumors. Therapeutic Ultrasound, 2011. 
 
Carlisle, R.C., Choi, J., Kostka, L., Bazan-Perergrino, M., Ulbrich, K., Seymour, L.W. and Coussios, C-C.: Ultrasound-enhanced delivery of polymer-coated oncolytic adenovirus for tumour growth inhibition. 
 
Wagstaffe, S.J., Arora, M., Schiffter, H.A. and Coussios, C.C.: Sonosensitive Nanoparticle Formulations for Cavitation-mediated Ultrasonic Enhancement of Local Drug Delivery. Proceedings of the Materials Research Society, Boston 2010. 
 
Conference Proceedings
 
A. Larrue and J.A. Noble, “Improved Nakagami imaging usinga combined estimator”, Proc. 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI) pp 1335-1338 (2012).
 
A. Cifor, L. Risser, D. Chung, E. M. Anderson, J. A. Schnabel. Hybrid feature-based log-demons registration for tumour tracking in 2-D liver ultrasound images. Proc. 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI) pp 724-727 (2012).
 
D Y Chung; A Larrue; S Rueda; P Boardman; F V Gleeson; E M Anderson.  Preliminary Study of Factors Influencing the Shape of Microwave Hepatic Tumor Ablation Zone With a 2.45-GHz Antenna in Vivo, RSNA 2012.
 
Larrue, A. and Noble, J.A.: Nakagami imaging with small windows. Proc. Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium, pp.887-890, 30th March- 2nd April 2011, Chicago, USA.
 
Wagstaffe, S.J., Schiffter, H.A., Arora, M. and Coussios, C-C.: Sonosensitive Nanoparticles for Controlled Instigation of Cavitation and Drug Delivery by Ultrasound. Proc. 11th International Symposium on Therapeutic Ultrasound, 11th–13th April, 2011, New York, USA.
 
Carlisle, R., Wagstaffe, S., Schiffter, H.A., Gilbert, R., Seymour, L. and Coussios, C-C.: Modification of Liposomal Drug Delivery Agents with Ultrasound Sensitive Functionality. Proc. 2nd Nanotoday, 11th-15th December 2011, Hawaii, USA.
 
Coviello, C., Kozick, R., Probert-Smith, P. and Coussios, C-C.: Reduction of Coherent and Incoherent Image Quality in Rectangular Boundary Arrays Due to Misalignment of Boundary Elements. Poster presentation, 2011 IEEE International Ultrasonics Symposium (IUS), 18th-21st October, 2011, Orlando, Florida, USA.
 
Schiffter, H.A., Wagstaffe, S., Arora, M. and Coussios, C-C.: Development of sonosensitive nanoparticles for cavitation-mediated targeted drug delivery. Proc. AAPS Annual Meeting and Exposition, 23rd–27th October 2011, Washington DC, USA.
 
Wagstaffe, S., Coussios, C-C. and Schiffter, H.A.: Sonosensitive Drug Carriers for Cavitation-Mediated Ultrasound Enhanced Drug Deliver. Proc. 2nd Nanotoday, 11th-15th December 2011, Hawaii, USA.
 
Wagstaffe, S., Schiffter, H.A. and Coussios, C-C.: Enhanced Nanoscale Surface Roughness to Facilitate Ultrasound-Induced Cavitation at Diagnostic Pressure Amplitudes. Proc. 2nd Nanotoday, 11th-15th December 2011, Hawaii, USA.
 
Wagstaffe, S.J., Arora, M., Schiffter, H.A. and Coussios, C.C.: Sonosensitive Nanoparticle Formulations for Cavitation-mediated Ultrasonic Enhancement of Local Drug Delivery. Proc. Materials Research Society, Volume 1370, 29th November-3rd December 2010, Boston, USA.
 
Arora, M., Schiffter, H., Manhas, V., Wagstaffe, S., and Coussios, C.C.: Biocompatible Solid Particles for Controlled Instigation of Cavitation during Therapeutic Ultrasound. J. Acoust. Soc. Am. (2010). (Invited lecture at the 2nd Pan-American/Iberian Meeting on Acoustics, Cancun, Mexico 2010.)
 
Coussios, C.C., Gyongy, M., Ritchie, R., Webb, I., Nandlall, S., Jackson, E., Arvanitis, C., Bazan-Peregrino, M., and Arora, M.: Passive Mapping for Real-Time Monitoring of Ultrasound Therapy. J. Acoust. Soc. Am. (2010). In press. (Invited lecture at the 2nd Pan-American/Iberian Meeting on Acoustics, Cancun, Mexico 2010.)
 
Meeting Abstracts 
 
C.M. Coviello , P. Probert-Smith and C-C. Coussios, “The Development of Cavitation-Enhanced Drug Delivery Utilizing A Conventional Diagnostic Ultrasound Imaging System and Sonosensitive Nanoparticles”, 12th International Symposium on Therapeutic Ultrasound, Heidelberg, Germany (2012).
 
R.C. Carlisle, J.J. Choi, L.W. Seymour and C.-C. Coussios, “Caviation-Enhanced Delivery of an Oncolytic Adenovirus for Tumour-Selective Cancer Therapy”, J. Acoust. Soc. Am. 131, 3246 (2012)
 
J.J. Choi, R. Carlisle, L. Seymour and C.-C. Coussios, “Passive Acoustic Mapping during Cavitation-Enhanced Virotherapy In Vivo”, 12th International Symposium on Therapeutic Ultrasound, Heidelberg, Germany (2012).
 
D. Holroyd, J.J. Choi, E. Mylonopoulou, D. Chung, P.J. Friend and C-C. Coussios, “Effects of Perfusion on Thermal and Cavitation Characteristics of HIFU Therapy Using A Novel Normothermic Extracorporeal Liver Perfusion Model”, 12th International Symposium on Therapeutic Ultrasound, Heidelberg, Germany (2012).
 
N. Hockham, S.J. Wagstaffe and C-C. Coussios, “Enhancement of HIFU Ablation by Use of Cavitation-Promoting Sonosensitive Nanoparticles”, 12th International Symposium on Therapeutic Ultrasound, Heidelberg, Germany (2012).
 
E. Mylonopoulou, J. Choi and C.-C. Coussios, “Spatio-Temporal Mapping of Drug Release from Thermally Sensitive Liposomes using Cavitation-Enhanced Ultrasonic Heating”, 12th International Symposium on Therapeutic Ultrasound, Heidelberg, Germany (2012).
 
S. Bhatnagar, C.-C. Coussios and H. Shiffter, “Molecular Transport Mechanisms in Ultrasound Assisted Transdermal Drug and Vaccine Delivery; A Mechanistic Study”, 12th International Symposium on Therapeutic Ultrasound, Heidelberg, Germany (2012).
 
Carlisle, R., Wagstaffe, S., Schiffter, H., Gilbert, R., Seymour, L. and Coussios, C-C.: Modification of Liposomal Drug Delivery Agents with Ultrasound Sensitive Functionality.  2nd Nano Today Symposium, Hawaii, Dec 2011
 
Wagstaffe, S.J. and Coussios, C-C.: Sonosensitive Drug Carriers for Cavitation-Mediated Ultrasound Enhanced Drug Delivery.  2nd Nano Today Symposium, Hawaii, Dec 2011
 
Wagstaffe, S.J., Schiffter, H.A. and Coussios, C-C.: Enhanced Nanoscale Surface Roughness to Facilitate Ultrasound-Induced Cavitation at Diagnostic Pressure Amplitudes.  2nd NanoToday Symposium, Hawaii, Dec 2011
 
Coviello, C., Faragher, S. and Coussios C.-C.: Robust Capon Beamforming for Passive Cavitation Mapping during HIFU Therapy, J. Acoust. Soc. Am., 2010
 
Wagstaffe, S., Arora, M. and Schiffter, H.: Biodegradable nanoparticles for drug delivery prepared by a new spray-drying process. Particles 2010, Orlando, FI (USA), 22.-26. May 2010
 
Coussios, C.C., Gyongy, M., Arvantis, C., Bazan-Peregrino, M., Rifai, B., Riche, R., and Arora, M.L: Passive Cavitation Mapping for Real-Time Monitoring of HIFU Ablation and Ultrasound-Enhanced Drug Delivery. 10th International Symposium on Therapeutic Ultrasound, Tokyo, Japan 2010.
 
Books
 
Rueckert, D., and Schnabel, J.A.: Medical Image Registration. Deserno, T.M.  Ed., Biomedical Image Processing Series on Biological and Medical Physics, Biomedical Engineering, Springer, 2011
 

Theme 3 – Treating cerebrovascular disease

Peer-reviewed original research articles
 
Tee, Y., Khrapichev, A., Sibson, N., Payne, S., & Chappell, M. (n.d.). Evaluating the Use of a Continuous Approximation for Model-Based Quantification of Pulsed Chemical Exchange Saturation Transfer (CEST). Journal of Magnetic Resonance, in press.
 
Chappell, M. A., Woolrich, M. W., Petersen, E. T., Golay, X., & Payne, S. J. (2012). Comparing model-based and model-free analysis methods for QUASAR arterial spin labeling perfusion quantification. Magnetic resonance in medicine  doi:10.1002/mrm.24372
 
Chappell, M. A., Woolrich, M. W., Kazan, S., Jezzard, P., Payne, S. J., & MacIntosh, B. J. (2012). Modeling dispersion in arterial spin labeling: Validation using dynamic angiographic measurements. Magnetic resonance in medicine  doi:10.1002/mrm.24260
 
Chappell, M. A., Okell, T. W., Payne, S. J., Jezzard, P., & Woolrich, M. W. (2012). A fast analysis method for non-invasive imaging of blood flow in individual cerebral arteries using vessel-encoded arterial spin labelling angiography. Medical Image Analysis. doi:10.1016/j.media.2011.12.004
 
Okell, T. W., Chappell, M. A., Schulz, U. G., & Jezzard, P. (2012). A kinetic model for vessel-encoded dynamic angiography with arterial spin labeling. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, n/a–n/a. doi:10.1002/mrm.23311
 
Chen H, Thompson H, Ventikos Y, Watton PN  (2012) Modelling the Influence of Haemodynamic Stimuli on Aneurysm Inception: An Investigation of 25 Clinical Cases, Invited Contribution to Special Issue on Vascular Biomechanics, Annals of Biomedical Engineering (to appear end of 2012).
 
Robertson A, Watton PN (2012), Computational Fluid Dynamics of Cerebral Aneurysms: Critical Reflections, Future Directions. American Journal of Neuroradiology, 10.3174/ajnr.A3192.
 
Watton, P.N., Chen, H., Selimovic, A., Thompson, H., Ventikos, Y.: Intracranial Aneurysms: Modelling Inception and Enlargement, GA. Holzapfel (ed.), Proceedings of IUTAM Symposium on Computer models in Biomechanics: from nano to macro, Springer-Verlag, Heidelberg, 2012
 
Watton P.N., Huang, H., Ventikos, Y.: Multiscale Modelling of Vascular Disease: Abdominal Aortic Aneurysm Evolution, In: L. Geris (ed.) Computational modelling in Tissue Engineering, Springer-Verlag, Heidelberg,  2012
 
Harvey, H., Suresh, V., Kang, W., Cooling, M.T., Watton, P.N., Hunter, P.J.: Multiscale modelling of intracranial aneurysms: Cell signalling, hemodynamics and remodelling, IEEE Transactions on Biomedical Engineering Letters, 58: 2974-2977
 
Desai, M.,  Ahmed, M., Darbyshire, A., You, Z., Hamilton, G. and Seifalian, A.M.: An aortic model for the physiological assessment of endovascular stent-grafts. Annals of Vascular Surgery, 2011
 
Ho, H., Suresh, V., Kang, W., Cooling, M.T., Watton, P.N. and Hunter, P.J.: Multiscale Modelling of Intracranial Aneurysms: Cell Signalling, Hemodynamics and Remodelling. IEEE Transactions on Biomedical Engineering Letter, 2011
 
Orlowski, P., Chappell, M.A., Sub Park, C., Grau, V. and Payne, S.: Modelling of pH dynamics in brain cells after stroke. Interface Focus, pages 408-416, 1(3): 2011. 
 
Schmid, H., Grytsan, A., Postan, E., Watton, P.N. and Itskov, M.: Influence of differing material properties in media and adventitia on arterial adaption – application to aneurysm formation and rupture. Computer Methods in Biomechanics and Biomedical Engineering, 2010
 
Seifalian, A.M., Desai, M., Eaton-Evans, J., Hillery, C., Raheleh, B., You, Z., Lu, J. and Hamilton, G.: AAA stent-grafts: Past Problems and Future Prospects. Annals of Biomedical Engineering, 2010
 
Zhou, X., You, Z. and Byrne, J.: Bio-inspired Leaf Stent for Direct Treatment of Cerebral Aneurysms. Smart Structures and Systems, 2010
 
Holland, EC, Watton, PN., Ventikos, Y.: Biological Fluid Mechanics: Integrative and Multiscale Computational Modelling in Comprehensive Biotechnology. Ed.M.M.Young. Elsevier. 
 
Conference Proceedings
 
Selimovic A, Ventikos Y and Watton PN. Investigating growth and remodelling hypotheses for patient-specific models of cerebral aneurysm evolution, 8th European Solid Mechanics Conference, Graz, Austria, July 9th-13th 2012.
 
Chappell, Michael A.; Okell, Thomas W.; Macintosh, Bradley J.; Jezzard, Peter; Payne, Stephen J. Accounting for Pre-Capillary Signal in Arterial Spin Labelling Perfusion Measurements Proc. Int. Soc. Magn. Reson. Med., 5th-11th May 2012, Melbourne, Australia.
 
Tee, Yee Kai; Khrapichev, Alexandr A.; Sibson, Nicola R.; Payne, Stephen J.; Chappell, Michael A. Analyse the Important Fitted Parameters Using Pulsed Fitting and Continuous CEST Approximation for Pulsed CEST Proc. Int. Soc. Magn. Reson. Med., 5th-11th May 2012, Melbourne, Australia.
 
Tee, Yee Kai; Khrapichev, Alexandr A.; Donahue, Manus J.; Sibson, Nicola R.; Payne, Stephen J.; Chappell, Michael A. Analyzing the Minimum Discretization of Pulses Required to Speed Up Model-Based Analysis for Pulsed CEST Proc. Int. Soc. Magn. Reson. Med., 5th-11th May 2012, Melbourne, Australia.
 
Chappell, Michael A.; Mehndiratta, Amit; Payne, Stephen J.; Calamante, Fernando Bayesian Model-Based Correction for Macro Vascular Signal in Dynamic Susceptibility Contrast Perfusion MRI  Proc. Int. Soc. Magn. Reson. Med., 5th-11th May 2012, Melbourne, Australia.
 
Okell, Thomas W.; Chappell, Michael A.; Jezzard, Peter Comparison of Non-Selective and Vessel-Encoded Pseudocontinuous Arterial Spin Labeling for Cerebral Blood Flow Quantification Proc. Int. Soc. Magn. Reson. Med., 5th-11th May 2012, Melbourne, Australia.
 
Mehndiratta, Amit; Macintosh, Bradley J.; Crane, David E.; Payne, Stephen J.; Chappell, Michael A. Improved Vascular Model -Based Analysis for DSC-MRI Perfusion Quantification Proc. Int. Soc. Magn. Reson. Med., 5th-11th May 2012, Melbourne, Australia.
 
Okell, Thomas W.; Chappell, Michael A.; Schulz, Ursula G.; Jezzard, Peter A Kinetic Model for Vessel-Encoded Dynamic Angiography with Arterial Spin Labeling Proc. Int. Soc. Magn. Reson. Med., 5th-11th May 2012, Melbourne, Australia.
 
Mehndiratta, Amit; Macintosh, Bradley J.; Crane, David E.; Payne, Stephen J.; Chappell, Michael A. Non-Parametric Quantification of Cerebral Haemodynamics from Dynamic Susceptibility Contrast MRI Proc. Int. Soc. Magn. Reson. Med., 5th-11th May 2012, Melbourne, Australia.
 
Piotr Orlowski, Michael Chappell, Chang Sub Park, Vicente Grau, Stephen Payne. Towards Personalized Treatment Planning for Ischemic Stroke Patients. Brain 2011 25th-28th May, Barcelona, Spain. 
 
Spranger K., Penrose J, Chianari A, Watton PN and Ventikos Y. Comparison of computational methods for simulating stent deployment, VPH 2012 Integrative approaches to biomedicine, London, Sept. 18th - 20th, 2012.
 
Watton PN, Ho H, Hunter P and Robertson A. Clinical Utility of Computational Modelling for Cerebral Aneurysms: The Road from Virtual to Reality, 8th European Solid Mechanics Conference, Graz, Austria, July 9th - 13th, 2012.
 
Chen H, Ventikos Y and Watton PN. Patient-specific modelling of cerebral aneurysm inception: The influence of haemodynamic stimuli, 8th European Solid Mechanics Conference, Graz, Austria, July 9th - 13th, 2012.
 
Selimovic A, Chen H, Penrose J, Ventikos Y and Watton PN. Low wall shear stress: a driving mechanism for cerebral aneurysm evolution ? Modelling development on patient-specific vasculature geometries. ANSYS UK User Conference, The Heritage Motor Centre, Gaydon, Nov. 9th - 10th, 2011.
 
Watton PN, Horner M, Penrose J, Selimovic A, Chen H and Ventikos Y. Patient-specific Modelling of Intracranial Aneurysm Evolution, ANSYS regional conference, Boston, Massachusetts, USA, Sept. 14th, 2011.
 
Watton, P.N., Robertson, A.: Intracranial Aneurysms: The clinical utility of computational modelling, 8th European Solid Mechanics Conference, 9th-13th July 2012, Graz, Austria
 
Selimovic, A., Ventikos, Y., Watton, P.N.: Growth and remodelling hypotheses for patient-specific models of cerebral aneurysm evolution, 8th European Solid Mechanics Conference, 9th-13th July 2012, Graz, Austria
 
Chen, H., Ventikos, Y., Watton, P.N: Investigating the haemodynamic environment prior to aneurysm formation: Novel methodology and study of 22 clinical cases, 8th European Solid Mechanics Conference, 9th-13th July 2012, Graz, Austria
 
Zajarias-Fainsod, D., Spranger, K., Ngoepe, M., Holland, E., Peach, T., Baptista, T., Chiarini, A., Penrose, J.M.T, Byrne, J.V., Watton, P.N., Ventikos, Y.: Modelling intracranial aneurysms treated with flow diverters: correlation of intra-aneurysm sac flow dynamics with thrombus evolution, 8th European Solid Mechanics Conference, 9th-13th July 2012, Graz, Austria
 
Grytsan, A., Watton, P.N., Holzapfel, G.A.: A Thick-Walled Fluid-Solid Growth Model of Abdominal Aortic Aneurysm Evolution, 8th European Solid Mechanics Conference, 9th-13th July 2012, Graz, Austria
 
Baptista, T., Watton, P.N., Holland, E., Penrose, J.M.T., Chiarini, A., Byrne, J., Reis, J.: Computational Fluid Dynamics in patients treated with flow-diverter devices, European Congress of Radiology, 1st - 5th March 2012, Vienna, Austria
 
Holland, E., Peach, T.W., Selimovic, A., Tully, B., Watton, P.N., Ventikos, Y.: Transport phenomena, Fluid Mechanics and Multiscale Modelling for Clinical Decision Support, International Conference on Fluid Dynamics, 14th - 16th November 2011, Paris, France
 
Chen, H., Thompson, H., Selimovic, A., Penrose, J., Ventikos, Y., Watton, P.N.: Investigating blood vessel haemodynamic environment prior to cerebral aneurysm formation: Novel methodology and study of 20 clinical cases. ANSYS UK User Conference, The Heritage Motor Centre, 9th - 10th November 2011, Gaydon
 
Selimovic, A., Chen, H., Penrose, J., Ventikos, Y., Watton, P.N.: Low wall shear stress: a driving mechanism for cerebral aneurysm evolution? Modelling development on patient-specific vasculature geometries, ANSYS UK User Conference, The Heritage Motor Centre, 9th - 10th November 2011, Gaydon
 
Watton, P.N., Horner, M., Penrose, J., Selimovic, A., Chen, H., Ventikos, Y.: Patient-specific Modelling of Intracranial Aneurysm Evolution, ANSYS regional conference, 20th October 2011, Minneapolis, Minnesota, USA
 
Baptista, T., Watton, P.N., Holland, E., Byrne, J., Reis, J.: Dinâmica de Fluídos Computacional aplicada a dois aneurismas intra-cranianos tratados com sistemas de derivação de fluxo, SILAN 2011, 10th-14th October 2011, Lisbon, Portugal
 
Watton, P.N., Horner, M., Penrose, J., Selimovic, A., Chen, H., Ventikos,Y.: Patient-specific Modelling of Intracranial Aneurysm Evolution, ANSYS regional conference, 30th August 2011, Chicago, Illinois, USA
 
Watton, P.N., Horner, M., Penrose, J., Selimovic, A., Chen, H., Ventikos,Y.: Patient-specific Modelling of Intracranial Aneurysm Evolution, ANSYS regional conference, 23rd August 2011, Santa Clara, California, USA
 
Chappell, M.A., Donahue, M.J., Tee, Y.K., Jezzard, P. and Payne S.J.: Quantitative Model-Based Analysis of Amide Proton Transfer MRI. Proc. Int. Soc. Magn. Reson. Med., 7th-13th May 2011, Montreal, Canada
 
Chappell, M.A., MacIntosh, B.J. and Payne, S.J.: Quantifying Bolus Dispersion In Arterial Spin Labelling To Monitor Haemodynamics In Vascular Disease. Brain 2011, 25th-28th May 2011, Barcelona, Spain
 
Chappell, M.A., MacIntosh, B.J., Woolrich, M.W., Jezzard, P. and Payne, S.J.: Modelling dispersion in Arterial Spin Labelling with Validation from ASL Dynamic Angiography. Proc. Int. Soc. Magn. Reson. Med., 7th-13th May 2011, Montreal, Canada
 
Chappell, M.A., Okell, T.W., Payne, S.J., Jezzard, P. and Woolrich, M.W.: Fast Analysis of Vessel Encoded ASL Perfusion and Angiographic Images for Clinical Applications. Proc. Int. Soc. Magn. Reson. Med., 7th-13th May 2011, Montreal, Canada
 
Chappell, M.A., Petersen, E.T., Woolrich, M.W.,  Golay, X. and Payne, S.J.: Full Model-Based Analysis of QUASAR Arterial Spin Labelling. Proc. Int. Soc. Magn. Reson. Med., 7th-13th May 2011, Montreal, Canada
 
Chen, H., Thompson, H., Selimovic, A., Ventikos, Y. and Watton, P.N.: Investigating blood vessel haemodynamic environment prior to cerebral aneurysm formation: Novel methodology and study of 20 clinical cases. Proc. Bioengineering 2011, 12th-13th September 2011, University of London, UK
 
Holland, E., Watton, P.N. and Ventikos, Y.: Modelling the Effect of Infra-Luminal Thrombus on Cerebral Aneurysm Evolution. Proc. IUTAM Symposium on Computer Models in Biomechanics: from Nano to Macro, 29th August-2nd September 2011, Stanford University, California, USA
 
Okell, T.W., Chappell, M.A., Schultz, U. and Jezzard, P.: Quantification of Vessel-Encoded Arterial Spin Labeling Dynamic Angiography with Auto-Calibration. Proc. Int. Soc. Magn. Reson. Med., Montreal, 7th-13th May 2011, Montreal, Canada
 
Selimovic, A., Chen, H., Ventikos, Y. and Watton, P.: Low wall shear stress: a driving mechanism for cerebral aneurysm evolution? Modelling development on patient-specific vasculature geometries. Proc. Bioengineering 2011, 12th-13th September 2011, University of London, UK
 
Tee, Y.K., Chappell, M.A., Xie, J. and Payne, S.J.: CEST Sensitivity Functions Based Sampling Schedule. Proc. Int. Soc. Magn. Reson. Med., 7th-13th May 2011, Montreal, Canada
 
Watton, P.N.: Computational Framework for patient-specific modelling of cerebral aneurysm evolution. Invited Lecture. Mini-Symposium: Computational biomechanics towards the overall human. 82nd Annual Meeting of the International Association of Applied Mathematics and Mechanics, 18th – 21st April 2011, Graz, Austria
 
Watton, P.N.: Modelling aneurysm evolution. Invited lecture. IUTAM Symposium on Computer Models in Biomechanics: From Nano to Macro, 29th August-2nd September 2011, Stanford University, California, USA
 
Watton, P.N.: Modelling the Evolution of Vascular Disease: Cerebral Aneurysms. Proc. 2011 ANSYS UK Conference, 9th November 2011, Gaydon, UK
 
Watton, P.N, Chen, H., Selimovic, A., Thompson, H., Horner, M., Penrose, J. and Ventikos, Y.: Patient-Specific Modelling of Intracranial Aneurysm Evolution. Proc. ASME 2011 Summer Bioengineering Conference, 22nd-25th June 2011, Famington, Pennsylvania, USA
 
Watton, P.N., Selimovic,A., Chen, H., Thompson, H., Ventikos, Y.: Patient-Specific Modelling of Cerebral Aneurysm Evolution. Proc. 2nd International Conference on Mathematical and Computational Biomedical Engineering (CMBE2011), 30th March – 1st April 2011, Washington D.C, USA
 
Watton, P.N., Selimovic, A., Chen, H. and Ventikos, Y.: Patient-specific Modelling of Intracranial Aneurysm Evolution.  Workshop on Interdisciplinary Biomedical Research, 18th-19th July 2011, University of Notre Dame London Centre, London, UK
 
Penrose, J.M.T., Selimovic, A., Ventikos, Y. and Watton, P.N.: Exploring the role of the pulsatile haemodynamic on the development of cerebral aneurysm for patient-specific geometries. Proc. NAFEMS conference, 8th-9th June 2010, Oxford, UK
 
Zhou, X. and You, Z.: A Novel Flow-diverting Stent for the Treatment of Intracranial Aneurysms: Design and Analysis. LINC Houston and ICS 2010, 13th -16th September 2010, Houston, USA
 
Meeting abstracts
 
Chappell, M.A., Okell, T.W., Payne, S.J., Jezzard, P., Woolrich, M.W. Fast Analysis of Vessel Encoded ASL Perfusion and Angiographic Images for Clinical Applications, Proc. Int. Soc. Magn. Reson. Med., Montreal, 2011.
 
Chappell, M.A., MacIntosh, B.J., Woolrich, M.W., Jezzard, P., Payne, S.J.: Modelling dispersion in Arterial Spin Labelling with Validation from ASL Dynamic Angiography, Proc. Int. Soc. Magn. Reson. Med., Montreal, 2011.
 
Chappell, M.A., MacIntosh, B.J., Payne, S.J.: Quantifying Bolus Dispersion in Arterial Spin Labelling to Monitor Haemodynamics in Vascular Medicine, Brain 2011, Barcelona.
 
Chappell, M.A., Donahue, M.J., Tee, Y.K., Jezzard, P., Payne, S.J.: Quantitative Model-Based Analysis of Amide Proton Transfer MRI, Proc. Int. Soc. Magn. Reson. Med., Montreal, 2011.
 
Chappell, M.A., Esben, Petersen Y, M., Woolrich, M.W., Golay X., Payne, S.J.: Full Model-Based Analysis of QUASAR Arterial Spin Labelling, Proc. Int. Soc. Magn. Reson. Med., Montreal, 2011.
 
Watton, P.N., Selimovic,A., Chen, H., Thompson, H., Ventikos, Y.: Patient-Specific Modelling of Cerebral Aneurysm Evolution, 2nd International Conference on Mathematical and Computational Biomedical Engineering (CMBE2011), Washington D.C, USA, March 30 - April 1, 2011
 
Holland E, Watton P.N., Ventikos Y.: Modelling the Effect of Infra-Luminal Thrombus on Cerebral Aneurysm Evolution. IUTAM Symposium on Computer Models in Biomechanics: from Nano to Macro, August 29-September 02 2011, Stanford University, California, USA.
 
Okell, T.W., Chappell, M.A., Schultz, U., Jezzard, P.: Quantification of Vessel-Encoded Arterial Spin Labelling Dynamic Angiography with Auto-Calibration, Proc. Int. Soc. Magn. Reson. Med., Montreal, 2011.
 
Tee, Y.K., Chappell, M.A., Xie, J., Payne, S.J.: CEST Sensitivity Functions Based Sampling Schedule, Proc. Int. Soc. Magn. Reson. Med., Montreal, 2011.
 
Watton P.N, Chen H., Selimovic A., Thompson H., Horner M., Penrose J., Ventikos Y.: Patient-Specific Modelling of Intracranial Aneurysm Evolution, Proceedings of the ASME 2011 Summer Bioengineering Conference, June 22-25, Nemacolin Woodlands Resort, Famington, Pennsylvania, USA.
 
Watton, P.N.: Computational Framework for patient-specific modelling of cerebral aneurysm evolution. Invited Lecture. Mini-Symposium: Computational biomechanics towards the overal human. 82nd Annual Meeting of the International Association of Applied Mathematics and Mechanics, Graz, Austria, April 18th - 21st, 2011.
 
Watton, P.N.: Modelling aneurysm evolution. Invited lecture. IUTAM Symposium on Computer Models in Biomechanics: From Nano to Macro, Stanford University, California, USA, August 29th - September 2nd, 2011.
 
Huang, H., Penrose J.M.T., Selimovic A., Ventikos Y.: Watton P.N.: Exploring the role of the pulsatile haemodynamic on the development of cerebral aneurysma for patient-specific geometries, NAFEMS conference, Oxford, UK, June 8th-9th, 2010.
 
Orlowski, P., Park, C.S, Chappell, M., Grau, V., and Payne, S.: Modelling of pH Dynamics in Brain Cells after Stroke. Presentation. VPH 2010, Brussels, September 2010.
 
Penrose J.M.T., Selimovic A., Ventikos Y., Watton P.N.: Exploring the role of the pulsatile haemodynamic on the development of cerebral aneurysma for patient-specific geometries, NAFEMS conference, Oxford, UK, June 8th-9th, 2010.
 
Robson MD., Ventikos, Y. and Watton, PN.: A Fluid-Solid-Structure Growth Model for Evolution of Abdominal Aortic Aneurysms. Poster presentation, 6th World Congress of Biomechanics, Singapore, 2010
 
Selimovic, A., Penrose, J., Bogunovic, H., Villa-Uriol, M.C., Ventikos, Y., Holzapfel G.A., Watton P.N.: A Computational Framework to Explore the Role of the Pulsatile Haemodynamics on Cerebral Aneurysm Development for Patient-Specific Arterial Geometries. Oral presentation of paper for the 6th World Congress of Biomechanics, Singapore, August 2010.
 
Selimovic, A., Watton, P.N., Ventikos, Y.: The role of pulsatility on the development of cerebral aneurysms; a computational modelling approach. Bioengineering 2010 conference, Nottingham 2010.
 
Watton, PN.: Modelling Aneurysm Evolution. Keynote Lecture, 6th World Congress of Biomechanics, Singapore, 2010
 
Zhou, X. and You, Z.: A Novel Flow-diverting Stent for the Treatment of Intracranial Aneurysms: Design and Analysis, abstract submission and oral presentation, LINC Houston and ICS 2010, Houston, Texas, 2010
 
Huang, H., Robson M.D., Ventikos, Y. and Watton, P.N.: A Fluid-Solid-Structure Growth Model for Evolution of Abdominal Aortic Aneurysms. Poster presentation, 6th World Congress of Biomechanics, Singapore, 2010.
 
Books
 
Watton, PN., Ventikos, Y., Holzapfel GA: Modelling Cerebral Aneurysm Evolution. Contributed book chapter in Biomechanics and Mechanobiology of Aneurysms. Springer-Verlag.
 
Robertson A, Watton PN, (2012) Mechanobiology of the Arterial Wall, In: Ed. Andrey Kuznetsov and Sid Becker (ed.) Modelling of Transport in Biological Media, Elsevier (in press).
 
Watton PN, Selimovic A, Chen H, Ventikos Y (2012) Patient Specific Modelling of Cerebral Aneurysm Evolution In: GA. Holzapfel (ed.), Proceedings of IUTAM Symposium on Computer models in Biomechanics: from nano to macro, Springer-Verlag, Heidelberg (in press).
 
Watton PN, Huang H, Ventikos Y (2012) Multiscale Modelling of Vascular Disease: Abdominal Aortic Aneurysm Evolution, In: L. Geris (ed.) Computational modelling in Tissue Engineering, Springer-Verlag, Heidelberg (in press).
 
Holland, E.C., Watton, P.N. and Ventikos, Y.: Biological Fluid Mechanics: Integrative and Multiscale Computational Modelling in Comprehensive Biotechnology. Young, M.M. et al Ed., Comprehensive Biotechnology 2nd edition, Elsevier, 2011. 
 
Watton, P.N., Ventikos, Y. and Holzapfel G.A.: Modelling Cerebral Aneurysm Evolution. Biomechanics and Mechanobiology of Aneurysms. McGloughlin, T. Ed., Series: Studies in Mechanobiology, Tissue Engineering and Biomaterials, Vol. 7, Springer-Verlag, 2011.