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BUBBL Facilities

Diagnostic and Therapeutic Ultrasound Laboratory Equipment

  • 2 large beamplotting tanks for fully automated 3-D acoustic characterization measurements.
  • 11 High Intensity Focussed Ultrasound (HIFU) transducers (0.25-3.3 MHz)
  • 9 Power Amplifiers (50-1000W) for HIFU delivery
  • 1 PVDF membrane, 8 PVDF needle, 2 PZT, and 1 fiber-optic hydrophones for validated charcterization of acoustic fields.
  • 3 different platforms for diagnostic ultrasound and therapy monitoring


Clinical Therapeutic Ultrasound Equipment

BUBBL is conducting a number of clinical trials in collaboration with the clinical HIFU unit in the Cancer Centre of the Oxford University Hospitals Trust, which is located on the same site as the BUBBL laboratory. The following clinical devices are in routine clinical use: 

Biopharmaceuticals and Encapsulation Equipment

  • FTS Lyostar I freeze-drying system
  • EHD (Electrohydrodynamic) spraying
  • Microfluidic devices for ultrasound contrast agent manufacturing
  • Virtis Advantage Plus freeze-drying system
  • Sorvall ST16R centrifuge
  • Buchi B205 Rotavapor
  • Furnace with temperature control (ThermoScientific)

Analytical Equipment

  • Varian Cary 50 UV/VIS spectrophotometer
  • Varian Prostar dual pump HPLC system with UV detector
  • Asymmetric Flow Field Flow Fractionation system (Postnova Analytics)
  • 880 nm laser for Raman scattering
  • Malvern Zetasizer Nano ZS ZEN3600
  • Malvern Mastersizer S laser light diffraction system
  • Mettler-Toledo DL39 Karl-Fischer-Titrator with Stombuli Oven
  • ATC Pycnomatic helium pycnometer