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Emma Bluemke

DPhil Student (1st Year) - DTC in Biomedical Imaging

Academic BackgroundEmma Bluemke

Emma graduated from The University of Western University (Ontario, Canada) with a BSc in Medical Biophysics. She began her imaging research career volunteering in the Parraga lab of Roberts Research Institute in 2014, on the topic of pulmonary hyperpolarized noble gas magnetic resonance imaging (MRI) and nitrogen washout. Following this, Emma was a member of Dr. Arash Zarrine-Afsar’s lab at the University of Toronto for two years, working on the development of mass spectrometry imaging coupled with surgical lasers for tumour research. She completed her undergraduate thesis with the Culham lab at the Brain and Mind Institute, focusing on artefact reduction in functional MRI (fMRI).  

In 2017, Emma was awarded a Medical Sciences Graduate Scholarship from the University of Oxford and New College to join the EPSRC & MRC Centre for Doctoral Training in Biomedical Imaging. The training involves one year of interdisciplinary training and two 3 month rotation projects. Emma completed her first rotation on using deep (machine) learning for MRI image analysis under the supervision of Professor Mark Jenkinson and Dr. Ana Namburete. In her second rotation, Emma joined the BUBBL group under the supervision of Professor Daniel Bulte and Professor Eleanor Stride, where she is focusing on MR Imaging of oxygen carriers in treatment of hypoxic tumours.

Peer-Reviewed Publications

M Woolman, A Gribble, E Bluemke, J Zou, M Ventura, N Bernards, M Wu, H Ginsberg, S Das, A Vitkin, A Zarrine-Afsar.  Optimized Mass Spectrometry Analysis Workflow with Polarimetric Guidance for ex vivo and in situ Sampling of Biological Tissues. Nature Scientific Reports 2017.

M Woolman, A Tata, E Bluemke, D Dara, H Ginsberg, A Zarrine-Afsar; An Assessment of the Utility of Tissue Smears in Rapid Cancer Profiling with Desorption Electrospray Ionization Mass Spectrometry (DESI-MS). J Am Soc Mass Spectr 2017.

M Woolman, A Tata, D Dara, J Meens, E D’Arcangelo, C Perez, S Prova, E Bluemke, H Ginsberg, D Ifa, A McGuigan, L Ailles, A Zarrine-Afsar. Rapid Determination of Tumor Stroma Ratio in Squamous Cell Carcinomas with Desorption ElectroSpray Ionization Mass Spectrometry (DESI-MS): A Proof-Of-Concept Demonstration. Analyst 2017.

J Bilkey, A Tata, T McKee, A Porcari, E Bluemke, M Ventura, M Eberlin, A Zarrine-Afsar; Variations in the Abundance of Lipid Biomarker Ions in Mass Spectrometry Images are Correlated to Tissue Density. Analytical Chemistry 2016.

A Tata, A Gribble, M Ventura, M Ganguly, E Bluemke, H Ginsberg, D Jaffray, D Ifa, A Vitkin, A Zarrine-Afsar; Wide-Field Tissue Polarimetry Allows Efficient Localized Mass Spectrometry Imaging of Biological Tissues. Chemical Science 2016.

A Tata, M Woolman, M Ventura, N Bernards, M Ganguly, A Gribble, B Shrestha, E Bluemke, H Ginsberg, A Vitkin, J Zheng, A Zarrine-Afsar.  Rapid Detection of Necrosis in Breast Cancer with Desorption ElectroSpray Ionization Mass Spectrometry. Nature Scientific Reports 2016.

Conference Proceedings

TJ Lindenmaier, E Bluemke, M Mura, C Licskai, L Mielniczuk, IA Cunningham, G Parraga; Three-Dimensional Segmentation of Pulmonary Artery Volume from Thoracic Computed Tomography Imaging. SPIE 2015.

F Guo, S Svenningsen, E Bluemke, M Rajchl, J Yuan, A Fenster, G Parraga; Automated Pulmonary Lobar Ventilation Measurements Using Volume-matched Thoracic CT and MRI. SPIE 2015.

 Poster & Oral Presentations

 Presented:

Dept. Medical Biophysics, University of Toronto 2016: Optimizing Mass Spectrometry Analysis: Polarimetric Guidance for Efficient ex vivo and in situ Sampling of Biological Tissues.

Radiation Physics Seminar 2016, University of Toronto:  Optimized Mass Spectrometry Analysis with Polarimetric Guidance for Efficient ex vivo and in situ Sampling of Biological Tissues. Princess Margaret Cancer Centre.

Dept. Medical Biophysics, University of Toronto 2015: Accelerating Margin Assessment: Wide-Field Tissue Polarimetry Allows Targeted Mass Spectrometry Profiling.

Radiation Physics Seminar 2015, University of Toronto: Accelerating Margin Assessment: Wide-Field Tissue Polarimetry Allows Targeted Mass Spectrometry Profiling. Princess Margaret Cancer Centre. Video-conferenced to Credit Valley Hospital, Lakeridge Health, Royal Victoria Hospital, Southlake Regional Health Centre.

London Health Research Day 2015: Relationship of Ventilation Heterogeneity in the Conducting and Acinar Airway Zones with 3He MRI in Elderly Never-Smokers.

Co-authored (did not attend):

American Association for Cancer Research Annual Meeting 2017: A Zarrine-Afsar, B Shrestha, A Tata, M Woolman, M Ventura, N Bernards, M Ganguly, H Ginsberg, J Zheng, E Bluemke; Rapid detection of necrosis in breast cancer with ex vivo and in situ mass spectrometry analysis methods.

American Thoracic Society 2015: E Bluemke, S Svenningsen, K Sheikh, G Paulin, DG McCormack, G Parraga; Relationship of Ventilation Heterogeneity in the Conducting and Acinar Airway Zones with 3He MRI in Elderly Never-Smokers.

American Thoracic Society 2015: S Svenningsen, D Capaldi, E Bluemke, G Paulin, C Davis, K Sheikh, DG McCormack, G Parraga; Lung Clearance Index and Hyperpolarized 3He MRI Ventilation Heterogeneity Measurements in non-CF Bronchiectasis and COPD. 

Google Scholar link: GSL