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Dr Joshua Owen

Post-Doctoral Researcher

Joshua Owen2Academic Background

Joshua graduated with an MSci in Chemistry (international programme) from University College London spending one year on exchange at the California Institute of Technology where he joined the Stoltz group for two terms in 2009 and obtained a Summer Undergraduate Research Fellowship working on natural product synthesis and the synthesis of an enzyme inhibitor.  

He then completed a Masters project at the Royal Institution of Great Britain during 2010 - 2011, where his research involved conjugating antibodies to magnetic nanoparticles which continued over the summer with Dr Nguyen Thanh and Professor Quentin Pankhurst at the Royal Institution (RI). 

Joshua started his doctoral studies in 2010 under Dr Eleanor Stride.  His research focused on the development of magnetic microbubbles as controllable drug delivery vehicles and ultrasound contrast agents as part of collaborative project with the RI and the Royal Free Hospital.  Joshua successfully defended his DPhil thesis in November 2014 and will join the Oxford Centre for Drug Delivery Devices (OxCD3) as a Post-Doctoral researcher.

Peer-Reviewed Publications

Carugo, D., Owen, J., Crake, C., Lee, J.Y. and Stride, E. (2015). Biologically and acoustically compatible chamber for studying ultrasound-mediated delivery of therapeutic compounds. Ultrasound Med. Biol. - in press.

Owen, J., Grove, P., Rademeyer, P. and Stride, E. (2014) The Effect of Blood on Targeted Drug Delivery Efficiency, J R Soc Interface, 11, 2014.0622.

Owen, J., Zhou, B., Rademeyer, P., Tang, M., Pankhurst, Q., Eckersley, R. and Stride, E. (2012) Understanding the Structure and Mechanism of Formation of a New Magnetic Microbubble Formation. Theranostics, 2, 1127-1139 (invited).

Owen, J., Pankhurst, Q. and Stride, E. (2012) Magnetic targeting and ultrasound mediated drug delivery: benefits, limitations and combination. Int. J. Hyperther, 28, 362-373.

Hosney, N.A., Mohamedi, G., Rademeyer, P., Owen, J., Wu, Y., Tang, M.X., Eckersley, R.J., Stride, E. and Kuimova, M.K. (2013) Mapping microbubble viscosity using fluorescence lifetime imaging of molecular rotors. Proc Natl Acad Sci USA, 110, 9225-9230. ISSN: 0027-8424.

Millard, T.P., Endrizzi, M., Rigon, L. Arfelli, F. Menk, R.H., Owen, J., Stride, E. and Olivo, A. (2013) Quantification of microbubble concentration through X-ray phase contrast imaging. Appl Phys Lett, 103, 114105.

Conference Presentations

Owen, J.W., Rademeyer, P. and Stride, E. (2014). The Influence of Blood on Targeted Microbubbles. Presented at the 14th International Symposium on Therapeutic Ultrasound, Las Vegas, 2-5 April 2014.

Owen, J. (2014). The Influence of Blood on Targeted Microbubbles. Presented at the 19th European Symposium on Ultrasound Imaging, Rotterdam, 23-24 January 2014.

Owen, J.W., Rademeyer, P. and Stride, E. (2013). Magnetic targeting of microbubbles at physiologically relevant flow rates. Presented at the 166th meeting of the Acoustical Society of America, San Francisco, 2-6 December 2013.

Crake, C., de Saint Victor, M., Coviello, C., Owen, J., Coussios, C. and Stride, E. (2013). Passive acoustic mapping of magnetic microbubbles in an in vitro flow model. Presented at the Joint Meeting of the Acoustical Society of America, The Canadian Acoustical Association and International Congress on Acoustics, Montreal, 2-7 June 2013.

Mohamedi, G., Hosny, N. Rademeyer, P., Park, Y., Owen, J., Pham, T., Joyce Wong, J., Kuimova, J. and Stride, E. (2013). Investigating the effect of fabrication method on the stability and acoustic response of microbubble agents. Presented at the Joint Meeting of the Acoustical Society of America, The Canadian Acoustical Association and International Congress on Acoustics, Montreal, 2-7 June 2013.

Owen, J.W., Rademeyer, P., Pankhurst, Q. and Stride, E. (2013). Imaging and retention of magnetic microbubbles at physiologically relevant shear rates. Presented at the 245th American Chemical Society Meeting, Colloid and Surface Chemistry Technical Symposium, New Orleans, 7-11 April 2013.

Owen, J. (2013). Magnetic microbubbles: controllable agents for ultrasound imaging and therapeutic delivery. Presented at the St. Catherine's College Biomedical Society Meeting, Oxford, 21 February 2013.

Owen, J., Rademeyer, P., Pankhurst, Q. and Stride, E. (2013). Magentic targeting of microbubbles at physiologically relevant flow rates. Presented at the 18th European Symposium on Ultrasound Contrast Imaging, Rotterdam, 16-18 January 2013.

Owen, J.,  Zhou, B., Hayotte, N., Tang, M., Pankhurst, Q., Eckersley, R. and Stride, E. (2012). Retention of magnetic microbubbles in a flow phantom. Presented at the 12th International Symposium on Therapeutic Ultrasound, Heidelberg, Germany, 10-13 June 2012.

Stride, E., Owen, J., Mulvana, H., Pankhurst, Q., Tang, M. and Eckersley, R. (2012). Magnetic microbubbles for localised imaging and drug delivery: Development, characterisation and preliminary application in vivo (invited). Presented at Acoustics 2012, Hong Kong, 14-18 May 2012.

Owen, J., Zhou, B., Hayotte, N., Tang, M., Pankhurst, Q., Eckersley, R. and Stride, E. (2012). Presented at the Magnetic Microbubbles Therapeutic Ultrasound Interest Group, University College London, 13 February 2012.

Awards

Young Investigator prize - European Symposium on Ultrasound Contrast Imaging held in Rotterdam, January 2015

Contact

Email:  joshua.owen@eng.ox.ac.uk

Phone: +44(0)1865 617760

Mailing Address: Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Old Road Campus Research Building, Headington, Oxford OX3 7DQ