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Dr Michael Gray

Senior Research Fellow in Clinical Therapeutic Ultrasound

Academic BackgroundDr Michael Gray

Michael joined the BUBBL group in September 2015 primarily to work on a Phase-1 clinical trial of ultrasound-mediated targeted drug delivery for treatment of liver cancer. His current research areas and interests include clinical translation of cavitation monitoring techniques and the use of sound and magnetism for targeted drug delivery.

Michael earned his doctorate from the Georgia Institute of Technology in 2015 after designing and demonstrating an ultrasonic system for deep tissue elastography.  Over the preceding 23 years, Michael was a research engineer and principal investigator at Georgia Tech, working in research areas including submarine sonar, cetacean soft tissue characterization, photoacoustics, fish hearing, and non-destructive structural evaluation. 

Recent Publications

 Gray, M.D., Lyon, P.C., Mannaris, C., Folkes, L.K., Stratford, M., Campo, L., Chung, D.Y.F., Scott, S., Anderson, M., Goldin, R., Carlisle, R., Wu, F., Middleton, M.R., Gleeson, F.V., and Coussios, C.C., “Focused ultrasound hyperthermia for targeted drug release from thermosensitive liposomes: results from a Phase 1 Trial”, Radiology (published online 15 Jan. 2019)

Mannaris, C., Bau, L., Grundy, M., Gray, M.D., Lea-Banks, H., Seth, A., Teo, B., Carlisle, R., Stride, E., and Coussios, C.C., “Microbubbles, nanodroplets and gas-stabilizing solid particles for ultrasound-medicated extravasation of unencapsulated drugs: an exposure parameter optimization study”, Ultrasound in Medicine and Biology, (published online 14 Jan. 2019)

Gray, M.D. and Coussios, C.C., “Broadband ultrasonic attenuation estimation and compensation with passive acoustic mapping”, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, (2018) 65(11): 1997-2011

Lyka, E., Coviello, C., Paverd, C., Gray, M.D. and Coussios, C.C., “Passive acoustic mapping using data-adaptive beamforming based on higher-orders statistics”, IEEE Transactions on Medical Imaging, (2018) 37(12): 2582-2592

Lyon, P.C., Gray, M.D., Mannaris, C., Folkes, L.K., Stratford, M., Campo, L., Chung, D.Y.F., Scott, S., Anderson, M., Goldin, R., Carlisle, R., Wu, F., Middleton, M.R., Gleeson, F.V., and Coussios, C.C., “TarDox: A Phase I trial investigating the safety and feasibility of ultrasound-triggered targeted drug delivery in liver tumours”, Lancet Oncology (2018) 19(8): 1027-1039

Barnsley, L.C., Gray, M.D., Beguin, E., Carugo, D., and Stride, E., “A combined magnetic-acoustic device for simultaneous, co-aligned application of magnetic and ultrasonic fields”, Advanced Materials Technologies, (2018) 3(7): 1800081

 

Gray, M.D., Lyka, E. and Coussios, C.C., “Diffraction effects and compensation in passive acoustic mapping”, IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control (2018) 65(2): 258-268

Holguin, S.Y., Gray, M.D., Joseph, P., Thadhani, N., and Prausnitz, M.R., “Photoporation using carbon nanotubes or intracellular delivery of molecules and its relationship to photoacoustic pressure”, Advanced Healthcare Materials (2018) 7(5): 1701007:1-10

 

 

Google Scholar Link: GSL

 

Contact

Email:

Phone: +44(0) 1865 617 692

Mailing address:

Institute of Biomedical Engineering

Old Road Campus Research Building

University of Oxford

OXFORD

OX3 7DQ

UK