Dr Michael Gray
Academic Background
Michael joined the BUBBL group in September 2015 primarily to work on a Phase-1 clinical trial of ultrasound-mediated targeted drug delivery for treatment of liver cancer. His current research areas and interests include clinical translation of cavitation monitoring techniques and the use of sound and magnetism for targeted drug delivery.
Michael earned his doctorate from the Georgia Institute of Technology in 2015 after designing and demonstrating an ultrasonic system for deep tissue elastography. Over the preceding 23 years, Michael was a research engineer and principal investigator at Georgia Tech, working in research areas including submarine sonar, cetacean soft tissue characterization, photoacoustics, fish hearing, and non-destructive structural evaluation.
Selected Recent Publications
Beguin, E., Gray, M.D., Logan, K.A., Nesbitt, H., Sheng, Y., Kamila, S., Barnsley, L.C., Bau, L., McHale, A.P., Callan, J.F., and Stride, E., “Magnetic microbubble mediated chemo-sonodynamic therapy using a combined magnetic-acoustic device”, J. Controlled Release, (2020) 317(10): 22-33, doi:10.1016/j.jconrel.2019.11.013
Gray, M.D., Stride, E., and Coussios, C.C., “Snap, Crackle, Pop: Theracoustic Cavitation,” Acoustics Today 15(1), Spring 2019, https://doi.org/10.1121/AT.2019.15.1.21
Gray, M.D., Lyon, P.C., Mannaris, C., Folkes, L.K., Stratford, M., Campo, L., Chung, D.Y.F., Scott, S., Anderson, M., Goldin, R., Carlisle, R., Wu, F., Middleton, M.R., Gleeson, F.V., and Coussios, C.C., “Focused ultrasound hyperthermia for targeted drug release from thermosensitive liposomes: results from a Phase 1 Trial”, Radiology, (2019) 291:232-238, https://doi.org/10.1148/radiol.2018181445
Gray, M.D. and Coussios, C.C., “Broadband ultrasonic attenuation estimation and compensation with passive acoustic mapping”, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, (2018) 65(11): 1997-2011, doi:10.1109/TUFFC.2018.2866171
Lyon, P.C., Gray, M.D., Mannaris, C., Folkes, L.K., Stratford, M., Campo, L., Chung, D.Y.F., Scott, S., Anderson, M., Goldin, R., Carlisle, R., Wu, F., Middleton, M.R., Gleeson, F.V., and Coussios, C.C., “TarDox: A Phase I trial investigating the safety and feasibility of ultrasound-triggered targeted drug delivery in liver tumours,” Lancet Oncology (2018) 19(8): 1027-1039, https://doi.org/10.1016/S1470-2045(18)30332-2
Google Scholar Link to Full Publication List: GSL
Contact
Email: michael.gray@eng.ox.ac.uk
Phone: +44(0) 1865 617 692
Mailing address:
Institute of Biomedical Engineering
Old Road Campus Research Building
University of Oxford
OXFORD
OX3 7DQ
UK