Dr Shamit Shrivastava
Shamit graduated with BTech in Mechanical Engineering in 2008 from the Indian Institute of Technology, India. For his undergraduate project he spent the summer and the winter of 2007 at Harvard Medical School and Massachusetts Institute of Technology Cambridge, USA. There working with Prof. Ali Khademhosseini he performed experimental and computational studies optimising the mechanical microenvironment of cells cultured in microfluidic devices for applications in Tissue Engineering.
Shamit started his doctoral studies in 2008 at the department of biomedical engineering in Boston University. He joined the biological physics group of Prof. Matthias Schneider in Oct 2009 where he provided the first evidence of two dimensional shock waves propagating along lipid interfaces. As part of his thesis he also established the biological relevance of this new phenomenon by demonstrating its coupling to local physicochemistry and enzymatic activity. Having obtained his doctorate in Jan 2014 Shamit continued to work in the Biological Physics group at Boston University before joining the Oxford Centre for Drug Delivery Devices (OxCD3) as a Post-Doctoral researcher in June 2015. At OXCD3 Shamit will be investigating the bio-effects of Shockwaves for applications in drug delivery.
LIST OF PUBLICATIONS
Bernhard Fichtl, Shamit Shrivastava, Matthias F Schneider 2016 “Protons at the speed of sound: Specific biological signaling from physics” accepted Scientific Reports
Shamit Shrivastava, Kevin Kang, Matthias F. Schneider 2015 “Solitary shock waves and adiabatic phase transition in lipid interfaces and nerves” Physical Review E Jan 2015 91 - 012715
Shamit Shrivastava and Matthias F. Schneider 2014 “Evidence for 2D Solitary Sound Waves in Lipid Controlled Interfaces and its Implications for Biological Signaling.” J. R. Soc. Interface vol. 11 no. 97 20140098
Shamit Shrivastava and Matthias F. Schneider 2013. “Opto-mechanical Coupling in Interfaces under Static and Propagative conditions and its Biological Implications.” PLoS ONE 8(7): e67524. doi:10.1371/journal.pone.0067524
H. C. Moeller, M. K. Mian, Shamit Shrivastava, B. G. Chung, Ali Khademhosseini; “A Microwell Array System for Stem Cell Culture: Effects of Material Properties and Cell Seeding Density”, Biomaterials 29 (2008) 752–763 DOI:10.1016/j.biomaterials.2007.10.030
A.Manbachi*, Shamit Shrivastava*, M. Cioffi, B. G. Chung, M. Moretti, M. Yliperttula, U. Demirci, Ali Khademhosseini; “Microcirculation within Grooved Substrates regulates Cell Positioning and Cell Docking inside Microfluidic Channels”, Lab on a Chip, February, 2008, 8, 747 - 754, DOI: 10.1039/b718212k. (*equal contribution)
Shrivastava, Shamit and Schneider, Matthias F. 2013 “ On the role of Solitary Elastic Pulses at Biointerfaces” Gordon Research Seminar, Soft Condensed Matter, New London, NH, USA
Schneider, Matthias F.; Nuschele, Stefan; Shrivastava, Shamit; Fillafer, Christian; Fichtl, Bernhard; Silman, Israel; Kaufmann, Konrad “From Thermodynamic States to Biological Function by Einstein's Approach to Statistical Physics” Conference Proceedings Biophysical Journal Biophysical Conference: Feb 2012
Shamit Shrivastava, Venkataramanan Soundararajan; “Smart Drug Delivery Capsule Design Using Shape Memory Polymers and Bio-polymers”, Processing Pharmaceutical Polymers, Paper 15, pp. 151-157, Basel, Switzerland,http://www.rapra.net/downloads/pharmapolymers.pdf, June 2007.
B.G. Chung, B.S Gillers, Shamit Shrivastava, Ali Khademhosseini; "Generation Of Microenvironments With Controlled Mechanical Properties For Analysis Of Mouse Embryonic Stem Cell Fate", The 2007 AIChE Annual Meeting: Annual Meeting of the American Electrophoresis Society (AES), #119g (T3011), Salt Lake City, Utah, http://aiche.confex.com/aiche/2007/techprogram/P98046.HTM, November 2007.
Shamit Shrivastava, S. Harishchandra, Venkataramanan Soundararajan, International Conference on Bio-informatics (INCOB), pp. 304, New Delhi, India, December 2006.
Shamit Shrivastava, "Simulation for Thermo-mechanical Behavior of a Shape Memory Alloy (SMA) Beam for Application in Micro Pumps", pp. 37-41, COMSOL Multiphysics Users Conference, Bangalore, India, http://cds.comsol.com/access/dl/papers/1688/Shrivastava.pdf, November 2006.
On physical origin of biological communication and nerve pulse propagation. EMBO Conference PhysCell Bad Staffelstein, Germany 2015
Solitary Shock waves in lipid interfaces and a new physical basis for biological signaling. Workshop on Physics of Excitatory Membranes (POEM) The Niels Bohr Institute, University of Copenhagen, Denmark 2016
HONORS AND AFFILIATIONS
Student Member Acoustical Society of America 2014-15
Cross-disciplinary Training in Nanotechnology for Cancer (XTNC) Fellowship, Boston University, Boston, USA 2010
Dean’s Fellowship, College of Engineering, Boston University, Boston, USA 2008
Screening Committee Member, MIT SLOAN Global Indus Technovators Awards, MIT, Cambridge, USA 2007
Graduate Teaching Faculty, Department of Biomedical Engineering, Boston University, USA
Solid Biomechanics (BE 426) 2009
Engineering Mechanics (EK 301) 2013