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Professor Robin O. Cleveland

Professor of Engineering Science; Tutorial Fellow at Magdalen College, Oxford

Professor Robin ClevelandContact

Phone: +44(0)1865 617 737
Mailing address: Institute of Biomedical Engineering, Old Road Campus Research Building, University of Oxford, Oxford OX3 7DQ, UK

Academic Background

Robin Cleveland is Professor of Engineering Science at the University of Oxford and Tutorial Fellow at Magdalen College, Oxford.  He received the PhD degree in Mechanical Engineering from the University of Texas at Austin where his doctoral research was on sonic boom propagation in the atmosphere.  At the completion of his PhD he was award the F.V. Hunt Fellowship of the Acoustical Society of America which he carried out at the University of Washington in Seattle studying shock wave lithotripsy – breaking of kidney stones by shock waves.  After two years in Seattle he joined the faculty at Boston University where he remained for fourteen years rising to the rank of Professor of Mechanical Engineering.  In 2011 he joined BUBL.  He carries out research in nonlinear acoustics with particular application to biomedical ultrasound.  Areas of research include: shock wave lithotripsy, high intensity focused ultrasound surgery for thermal ablation,  nonlinear distortion of B-mode diagnostic ultrasound, the development of shelled microbubble for ultrasound theranostics (targeted imaging and drug-delivery).

Awards and Prizes

  • Royal College of Surgeons of Edinburgh, Guest Lecturer at World Congress of Endourology, London (2015).Royal College of Surgeons of Edinburgh, Guest Lecturer at World Congress of Endourology, London (2015).
  • Plenary Speaker, International Symposium on Nonlinear Acoustics, Lyon, France (2015).
  • Keynote Speaker, Joint 11th Congrès Français d'Acoustique and the Annual Institute of Acoustics Meeting (2012).
  • Paper of the Year IEEE Trans. on UFFC (2006).
  • Teacher of the Year, Mechanical Engineering, Boston University (2009). 
  • ASA Bruce Lindsey Award (2000) 
  • ASA Hunt Post-Doctoral Fellowship in Acoustics (1995-6).

Selected Recent Publications

  •  A. Y. Ammi, R. O. Cleveland, J. Mamou, G. I. Wang, S. L. Bridal, W. D. O ’Brien, Jr, “Ultrasonic contrast agent shell rupture detected by inertial cavitation and rebound signals,” IEEE Trans. on UFFC 53:126-136 (2006).
  • R.O. Cleveland, P.V. Chitnis, S.R. McClure, “Acoustic Field of a Ballistic Shock Wave Therapy Device,” Ultrasound Med. and Biol. 33:1327-1335  (2007).
  • Y. Jing and R. O. Cleveland, “Modeling the propagation of nonlinear three-dimensional acoustic beams in inhomogeneous media,” J. Acoust Soc. Am. 122:1352—1364 (2007).
  • J. Huang, J. Triedman, N. V. Vasilyev, Y. Suematsu, R. O. Cleveland, P. E. Dupont, “Imaging artifacts of medical instruments in sonographically guided interventions,” J. Ultrasound in Medicine 26:1303-1322 (2007).
  • T.G. Leighton and R.O. Cleveland, “Lithotripsy,” Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 224(2): 317-342 (2010).
  • J. Condliffe, H. A. Schiffter, R. O. Cleveland, C-C. Coussios, “An Acoustic Microscopy Technique to Assess Particle Size and Distribution Following Needle-free Injection,” J. Acoust. Soc. Am. 127: 2252-2261 (2010).
  •  N. J. Manzi, P. V. Chitnis, R.G. Holt, R.A. Roy, R. O. Cleveland, B Riemer and M. Wendel, “Detecting cavitation in mercury exposed to a high-energy pulsed proton beam,”  J. Acoust. Soc. Am. 127(4): 2231-2239 (2010).
  •  W. J. Duncanson, K. Oum, J. R.Eisenbrey, R. O. Cleveland, M. A. Wheatley and J. Y. Wong, “Targeted binding of PEG-lipid modified polymer ultrasound contrast agents with tiered surface architecture” J. Biotechnology and Bioengineering, 106(3):501-6, (2010).
  •  P. Lai, J. R. McLaughlan, A. B. Draudt, T. W. Murray, R.O. Cleveland and R. A. Roy, “Real time monitoring of high intensity focused ultrasound lesion formation using acousto-optic sensing” Ultrasound. Med in Biol, 37: 239-252 (2011).
  • J. J. Rassweiler, T. Knoll, Kai-Uwe Köhrmann, J. A. McAteer, J. E. Lingeman, R. O. Cleveland, M. R. Bailey, C. Chaussy, “Shock wave technology and application – an update,” Eur. Urol. 59:784-796 (2011). 
  • L. E. Goldstein, A. M. Fisher, C. A. Tagge, X.-L. Zhang, L. Velisek, J. A. Sullivan, C. Upreti, J.M. Kracht,  M. Ericsson, M. Wojnarowicz,  C. J. Goletiani, G. M. Maglakelidze, N. Casey, J. A. Moncaster, O Minaeva, R.D. Moir, C.J. Nowinski, R.A. Stern, R.C. Cantu, J. Geiling, J. K. Blusztajn, B. L. Wolozin, T. Ikezu, T.D. Stein, A.E. Budson,  N.W. Kowall, D. Chargin, A. Sharon, S. Saman, G.F. Hall, W.C. Moss, R. O. Cleveland, R. E. Tanzi, P. K. Stanton, A, C. McKee “Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model,” Science Translational Medicine 4(134):1—16 (2012) PMCID: PMC3739428.

  • C. Jensen, R.O. Cleveland, C-C Coussios, Real-time temperature estimation and monitoring of HIFU ablation through a combined modeling and passive acoustic mapping approach, Physics in Medicine and Biology, 58: 5833-5850  (2013).

  • M. T. Adams, Q. Wang, R. O. Cleveland and R. A. Roy, Thermal dose dependent optical property changes of ex vivo chicken breast tissues between 500 and 1100 nm, Physics in Medicine and Biology 59(13): 3249-60 (2014).

  • V. Suomi, D. Edwards, R.O. Cleveland, Optical quantification of harmonic acoustic radiation force excitation in a tissue-mimicking phantom, Ultrasound in Med. Biol. 41: 3216-32 (2015)

  • Y. Park, T. A. Pham, C. Beigie, M. Cabodi, R. O. Cleveland, J. O. Nagy, and J. Y. Wong, Micro-Oil Droplets with Polymerizable Lipid Coating as Potential Drug Carriers, Langmuir 31:9762-70 (2015).

  • S.R. Harrogate, L.M.S. Yick, J.C. Williams Jr., R.O. Cleveland, B.W. Turney, Quantification of the range of motion of kidney and ureteric stones during shockwave lithotripsy in conscious patients.  J. Endourology 30(4): 406-410 (2016).

  • S. R. Faragher, R. O. Cleveland, S. Kumar, O.J. Wiseman and B. W. Turney In-vitro assessment of clinical shock wave lithotripsy technologies, J. Endourology 30(5): 560-565 (2016).

  • Sandra Nwokeoha, Robert Carlisle, Robin Cleveland, The Application of Clinical Lithotripter Shock Waves on RNA Nucleotide Delivery to Cells, Ultrasound Med Biol 42:2478-2492 (2016).

  • Shan Qiao, Edward Jackson, Constantin C. Coussious, Robin O. Cleveland, Simulation of nonlinear propagation of biomedical ultrasound using PZFlex and the KZK Texas code, Accepted J. Acoust. Soc. Am. (2016).

  • V. Suomi, Visa; Y. Han; D. Edwards; E. Konofagou,; R.O. Cleveland, “The effect of temperature dependent tissue parameters on acoustic radiation force induced displacements" Accepted Physics Med Biol (2016).