Guoying Zhou

Current Position: Post-Doctoral Research Assistant

Supervisors: Prof Zhanfeng Cui, Prof Cathy Ye and Dr Julian Dye

Contact Information: Institute of Biomedical Engineering

Department of Engineering Science

Old Road Campus Research Building

University of Oxford

Headington

Oxford OX3 7DQ, UK

Tel: +44 (0) 18 6561 7914

E-mail: guoying.zhou@eng.ox.ac.uk

Research Interests: Bio-intelligent skin scaffolds

Biocompatible biomaterials

Cell-material interaction

Background:

Education:

PhD (Magna cum Laude) in Biomaterial Science, 09.2011 –05.2017

Martin Luther University of Halle-Wittenberg, Halle, Germany.

PhD topic: In vitro studies on inflammatory potential of biomaterials with development of anti- inflammatory strategies

MSc (first class) in Polymer Chemistry and Physics, 09.2008 –06.2011

University of Science and Technology of China, Hefei, China.

Master topic: Synthesis of poly(ethylene glycol) containing copolymers and study of their protein resistance properties

BSc (first class) in Polymer Materials and Engineering, 10.2004 –06.2008

University of Jinan, Jinan, China.

Awards and Scholarships:

ESAO-Wichtig Research Award for best peer-reviewed publication (2017).
Scholarship from Federal Ministry of Education and Research (BMBF) of Germany (2016-2017).
Scholarship from German Academic Exchange Service (DAAD) (2015).
Scholarship from China Scholarship Council (CSC) (2011-2015).

Publications:

Journal Papers

[1] Zhou GY, Liedmann A, Chatterjee C, Groth T. In vitro study of the host responses to model biomaterials via a fibroblast/macrophage co-culture system. Biomaterials Science, 2017, 5(1): 141-152.

[2] Zhou GY, Niepel MS, Saretia S, Groth T. Reducing the inflammatory responses of biomaterials by surface modification with glycosaminoglycan multilayers. J Biomed Mater Res Part A. 2016; 104, 493-502.

[3] Zhou GY, Al-khoury H, Groth T. Covalent immobilization of glycosaminoglycans to reduce the inflammatory effects of biomaterials. Int J Artif Organs. 2016; 39, 37-44.

[4] Zhou GY, Loppnow H, Groth T. A macrophage/fibroblast co-culture system using a cell migration chamber to study inflammatory effects of biomaterials. Acta Biomaterialia. 2015; 26:54-63.

[5] Zhou GY, Groth T. Host responses to implants and the design of anti-inflammatory biomaterials – a short review. To be submitted to Journal of bioactive and compatible polymers.

[6] Kowitsch A, Zhou GY, Groth T. Medical Application of Glycosaminoglycans - A Review. J Tissue Eng Regen Med, 2017, DOI: 10.1002/term.2398.

[7] Li Z, Kowitsch A, Zhou GY, Groth T, Fuhrmann B, Niepel M, et al. Enantiopure chiral poly(glycerol methacrylate) self-assembled monolayers knock down protein adsorption and cell adhesion. Adv Healthc Mater. 2013; 2:1377-87.

[8] Zhou GY, Ma CF, Zhang GZ. “Synthesis of Polyurethane-g-Poly(ethylene glycol) Copolymers by Macroiniferter and Their Protein Resistance”, Polym. Chem., 2011, 2(6), 1409–1414.

[9] Ma CF, Zhou GY, Zhang GZ. “Protein Resistance of Polyurethane with Hydrophilic and Hydrophobic Soft Segments”, J. Polym. Sci., Part B: Polym. Phys., 2010, 48(18), 1987–1993.

Conference Presentations:

Published abstracts

[1] Zhou G, Loppnow H, Groth Th. Characterization of inflammatory potential of biomaterials by using a novel macrophage / fibroblast co-culture system. The International Journal of Artificial Organs, 37 (8), 2014, p. 616.

[2] Zhou G, Jurado M, Köwitsch A, Schlenker S, Fuhrmann B, Groth Th. Development of an in vitro inflammation model by patterned co-cultures of macrophages and human fibroblasts. BioNanomat, 13(1-4), 2012, p. 216.

[3] Li Z, Kowitsch A, Zhou G, Groth T, Fuhrmann B, Amado E, et al. Chirality of poly(glycerol methacrylate) brushes affects protein adsorption and cell adhesion. Abstr Pap Am Chem Soc. 2013; 245.

Posters:

[1] Zhou G, Al-Khoury H, Saretia S, Groth Th. Reduced inflammatory response to biomaterials after glycosaminoglycan immobilization. Summer school on Biomaterilas and Regenerative Medicine. 4th – 9th July, 2016, Riva del Garda, Trentino Region, Italy.

[2] Zhou G, Loppnow H, Groth Th. Characterization of inflammatory potential of biomaterials by using a novel macrophage / fibroblast co-culture system. 41st Congress of European Society for Artificial Organs, 17th - 20th September, 2014, Rome, Italy

[3] Zhou G, Schlenker S, Fuhrmann B, Loppnow H, Groth Th. Development of a Macrophage/Fibroblast Co-culture System for Characterization of Inflammatory Potential of Biomaterials. Advanced summer school: inflammation/repair interface, 25th – 28th June, 2013, Porto, Portugal

[4] Zhou G, Jurado M, Köwitsch A, Schlenker S, Fuhrmann B, Groth Th. Development of an in vitro inflammation model by patterned co-cultures of macrophages and human fibroblasts. Annual Meeting of the German Society for Biomaterials, 1st – 3rd November, 2012, Hamburg, Germany

[5] Ma C, Zhou G, Zhang G. Effect of Microphase Separation on the Protein Resistance of a Polymeric Surface. Polymer academic report, August, 2009, Tianjin, China.

Oral presentations:

[1] Zhou G, Saretia S, Al-Khoury H, Groth T. Glycosaminoglycans as efficient tool to reduce inflammatory response to biomaterials for anti-inflammation targeting. 7th International Congress BioNanoMed 2016 – Nanotechnology enables Personalized Medicine, 6th – 8th April, 2016, Krems, Austria.

[2] Zhou G, Al-Khoury H, Saretia S, Groth T. Immobilization strategies for glycosaminoglycans on biomaterials for anti-inflammatory purposes. XLIII Annual Congress of the European Society for Artificial Organs. 14th – 17th September, 2016, Warsaw, Poland.