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Yichen Li

Current position          Part-time research assistant (Stem Cell Culture)

College                         St. Anne’s college

Supervisors                 Hua Ye, Zhanfeng Cui and Francis Szele

Contact Information    56 Woodstock Rd,

                                      St. Anne’s College

                                      Telephone:  01865 272196 

                                      E-mail:

 

Research Interests

In vitro stem cell strategies to study neural development in adolescent-onset schizophrenia

 

Background

 

Education

DPhil candidate in Physiology, Anatomy and Genetics, University of Oxford

 

Work Experience

Research Assistant at University of Southern California

 

Awards and Scholarships

Clarendon Scholarship

 

Patents

Protection of ALS and FTD patient neurons by restoring c9orf72 levels and modulating endosomal trafficking (No. 62/184732)

 

Publications

Journal Papers

Y. Shi*, S. Lin*, K. A. Staats, Y. Li, W. H. Change, S. T. Hung, E. Hendricks, G. R. Linares, Y. Wang, E. Y. Son, X. Wen, K. Kisler, B. Wilkinson, L. Menendez, T. Sugawara, P. Woolwine, M. Huang, M. J. Cowan,B. Ge, N. Koutsodendris, K. P. Sandor, J. Komberg, V. R. Vangoor, K. Senthilkumar, V. Hennes, C. Seah, A. R. Nelson, T. Y. Cheng, S. J. J. Lee, P. R. August, J. A. Chen, N. Wisniewski, V. Hanson-Smith, T. G. Belgard, A. Zhang, M. Coba, C. Grunseich, M. E. Ward, L. H. van den Berg, R. J. Pasterkamp,  D. Trotti, B. Z. Zlokovic and J. K. Ichida. Haploinsufficiency Leads to Neurodegeneration in C9ORF72 ALS/FTD Human Induced Motor Neurons. Nature Medicine, 2018 [in press]

K. Babos, K. Kisler, Y. Li, Y, Shi, B. V. Zlokovic, and J. Ichida. p53 inhibits the direct conversion of fibroblasts into motor neurons [submitted]

R. W. H. Verwer, A. A. Sluiter, R. A. Balesar, J. C. Baaijen, P. C. de Witt Hamer, D. Speijer, Y. Li, D. F. Swaab. Injury Response of Resected Human Brain Tissue In Vitro. Brain Pathology (25), 2015, 454-468.

 

Conference Proceedings

Y. Li, W. Haenseler, S. Cowley, A. James, P. M. Devesa, E. Nivet, F. P. Féron, A. Mackay-Sim, B. Sun and F. Szele. Dissecting the mechanisms underlying adolescent-onset schizophrenia using patient-derived cortical neurons and microglia. Cold Spring Harbor Laboratory Meetings & Courses Program. Cold Spring Harbor, NY: Development & 3D modelling of the human brain, 2017. Online.

P. J. Grover, Y. Li, P. J. Hellyer, R. Leech, D. J. Sharp. How does mechanism of injury relate to patterns of white matter tract damage following traumatic brain injury? Program No. 011.06. 2013 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2013. Online.

 

Collaborators    Sally Cowley, Steven Chance, Emmanuel Nivet, Francois Feron, Alan Mackay-Sim


Teaching             St. Anne’s College, 1st year Medicine;

                             Summer school, neuroanatomy