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Zhaohui Li

Current Position           Senior Researcher in Translational Stem Cell Technology

Contact Information     Institute of Biomedical Engineering
                                    Department of Engineering Science
                                    Old Road Campus Research Building
                                    University of Oxford
                                    Oxford
                                    OX3 7DQ

                                    Tel: +44 1865 617653
                                    E-mail: Zhaohui.li@eng.ox.ac.uk                             
                                    https://uk.linkedin.com/in/zhaohui-li-b4826127 


Research Interests

Zoe is a goal-oriented R&D leader with over 12 years of experience in stem cell and tissue engineering research and biotech start-ups, leading development of advanced three-dimensional (3D) perfused cell culture platforms and bioprocessing engineering products for regenerative medicine and cell therapy research and commercialisation

 

Background

Education:

2007 Wolfson College, Oxford University, DPhil in Tissue Engineering

Thesis topic: Molecular markers for monitoring engineered tissue growth using microdialysis

1989 School of Chemical Engineering, Dalian University of Technology, China, BEng in Polymer Chemical Engineering    


Work Experience

Dec 2012 – Now Senior Researcher in Translational Stem Cell Technology, CRMI Centre, Institute of Biomedical Engineering, Oxford University

Nov 2013 – Now Chief Operation Officer at Oxford MESTAR Ltd, Oxford Science Park

Oct 2009 – Nov 2012 Head of Biology at CN Bio innovation (previously Zyoxel  Ltd) Begbroke Science Park

Sep 2007 – Sep 2009 Post-doc Researcher at Oxford Stem Cell Institute, Oxford University

Jan 2003 – Sep 2003 Academic visitor in Engineering Department, Oxford University

July 1989 – June 2002 Quality-control Engineer at Liaoning Exit & Entry Inspection and Quarantine Bureau (CIQ), China

 

Publications

Journal Papers

  1. Xiao Wan, Zhaohui Li, Hua Ye, Zhanfeng Cui. Three-dimensional perfused tumour spheroid model for anti-cancer drug screening. Biotechnology Letters. Accepted.
  2. Yueting Wu, Jiachen Sun, Julian George, Qingxi Liu, Hua Ye, Dan Ge, Yang Liu, Yaozhou Zhang, Zhanfeng Cui, Zhaohui Li. Study of neuroprotective function of Ginkgo Biloba extract (EGb761) derived-flavonoid monomers using a three-dimensional stem cell-derived neuron model. Biotechnology Progress. Accepted.
  3. Z Li, Z Cui. Three-dimensional perfused cell culture. Biotechnology Advances 2014, 32(2):243-54.
  4. Z Li, H Sun, J Zhang, H Zhang, F Meng, Z Cui. Development of in vitro 3D TissueFlex Islet model for diabetic drug efficacy testing. PLOS ONE 2013, 8(8):e72612.
  5. Ferraz ERA, Li Z, Boubriak O, de Oliveira DP. Hepatotoxicity assessment of the Azo dyes disperse orange 1 (DO1), disperse red 1 (DR1) and disperse red 13 (DR13) in HepG2 cells. Journal Toxicology and Environmental health Part A 2012, 75:16-17, 991-999.
  6. Li Z, Kreiner M, Edrada-Ebel R, Cui ZF, van der Walle CF, Mardon HJ. Perfusion culture enhanced human endometrial stromal cell growth in alginate-multivalent integrin α5β1 ligand scaffolds. J Biomed Mater Res A. 2011, 99(2):211-20.
  7. Li Z, Kreiner M, van der Walle CF, Mardon HJ. Clustered integrin α5β1 ligand displays model fibronectin-mediated adhesion of human endometrial stromal cells. Biochem Biophys Res Commun. 2011; 407(4):777-782.
  8. Kreiner M, Li Z, Beattie J, Kelly SM, Mardon HJ, van der Walle CF. Self-assembling multimeric intergrin α5β1 ligands for cell attachment and spreading. Protein Engineering, Design & Selection. 2008; 21(9): 553-560.
  9. Li Z, Hughes D, Urban JPG, Cui ZF. Effect of Transmembrane Pressure on recovery in microdialysis. Journal of Membrane Science. 2008; 310: 237-245.
  10. Li Z, Cui ZF. Application of microdialysis on Tissue Engineering monitoring. Progress of Natural Science. 2008; 18: 503-511.
  11. Li Z, Boubriak OA, Urban JPG, Cui ZF. Microdialysis for monitoring the process of functional tissue culture. International Journal of Artificial Organs. 2006; 29(9): 858-865.
  12. Guan J, Urban JP, Li Z, Ferguson DJ, Gong CY, Cui ZF. Effects of rapid cooling on articular cartilage. Cryobiology. 2006; 52(3): 430-439.

 

Book Chapters

  1. Li Z.  In vitro micro-tissue and –organ models for toxicity testing. In: M Moo-Young (Ed): Comprehensive Biotechnology 2e, Elsevier, ISBN 978-0-08-088504-9, 2011, Vol 5, pp551-563.
  2. Li ZH, Boubriak OA, Urban JP, Cui ZF. Tissue-Engineering Monitoring Using Microdialysis. In: J Polak (Ed): Advances In Tissue Engineering, World Scientific Publishing and Imperial College Press, ISBN 978-1-84816-182-5 1-84816-182-4, 2008, pp 401-420.