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JOURNAL PAPERS (see below for Book Chapters and Patents)

3D finite element formulation for mechanical-electrophysiological coupling in axonopathy. Man Ting Kwonga, Fabio Bianchi, Majid Malboubi, Julián Andrés García-Grajales, Lina Homsi, Mark Thompson, Hua Ye, Ludovic Noels, Antoine Jérusalem. Science Direct. 2018

Evidences of the Effect of GO and rGO in PCL Membranes on the Differentiation and Maturation of Human Neural Progenitor Cells. Sandra Sánchez‐González, Nazely Diban, Fabio Bianchi, Hua Ye,  Ane Urtiaga. Macromolecular Bioscience. 2018

Assembly of 2D MXene Nanosheets and TiO2 Nanoparticles for Fabricating Mesoporous TiO2-MXene Membranes. Zhi Xu, Sun Y., Zhuang Y., Jing W., Ye H., Cui Z. Journal of membrane science. 2018 Volume 564, October, Pages 35-43. 

Direct electrospinning of poly(vinyl butyral) onto human dermal fibroblasts using a portable device. Chui C-Y, Mouthuy P-A, Ye H. Biotechnol Lett. 2018 40: 737. 

Electrosprayed genipin cross-linked alginate-chitosan microcarriers for ex vivo expansion of sesenchymal stem cells. Chui C-Y, A.Odeleye, L.Nguyen, N.Kasoju, E.Soliman, H.Ye. J Biomed Mater Res Part A. 2018 00:1–12.

Manufacture and Characterization of EmDerm – a novel hierarchically structured bio-intelligent scaffold for tissue regeneration. Xuxin Lim,  Matt Potter, Zhanfeng Cui & Julian Dye. Journal of Materials Science: Materials in Medicine. 2018 Jun 5;29(6):79.

3D-printed membrane for guided tissue regeneration. Lobat Tayebi, Morteza Rasoulianboroujeni, Keyvan Moharamzadeh, Thafar KD Almela, Zhanfeng Cui and Hua Ye. Materials Science and Engineering: C. 2018 Volume 84, Pages 148-158.

3D-Printed membrane as an alternative to amniotic membrane for ocular surface/conjunctival defect reconstruction: an in vitro & in vivo study. Dehghani, Rasoulianboroujeni M., Ghasemi1 H., Keshel S.H., Nozarian Z., Hashemian M.N., Ghanavati M.Z., Latifi G., Ghaffari R., Cui Z., Ye H., Tayebi  L. Biomaterials. 2018 Volume 174, Pages 95-112. 

3d-printed thick structured gelatin membrane for engineering of heterogeneous tissues. Lobat Tayebi, Morteza Rasoulianboroujeni , Zhanfeng Cui and Cathy H Ye. Journal of Materials Letters. 2018 Volume 217,  Pages 39-43.

Strain partitioning between nerves and axons: estimating strain using sodium channel staining in intact peripheral nerves. Fabio Bianchi, Ruby Sedgwick, Hua Ye, Mark Thompson. Journal of Neuroscience Method. 2018 Volume 309, 1 November 2018, Pages 1-5.

Engineered method for directional growth of muscle sheets on electrospun fibres. Soliman, E, Bianchi F, Sleigh JN, George JH, Cader MZ, Cui Z, Ye H. Journal of Biomedical Materials Research: Part A. 2018 106A:1165–1176.

Aligned electrospun fibres for neural patterning. Soliman, E, Bianchi F, Sleigh JN, George JH, Cader MZ, Cui Z, Ye H. Biotechnology Letters. 2018 40: 601.

Differential and Interactive Effects of Substrate Topography and Chemistry on Human Mesenchymal Stem Cell Gene Expression. Qiongfang Li, Bo Zhang, Naresh Kasoju, Jinmin Ma, Aidong Yang, Zhanfeng Cui, Hui Wang, Hua Ye. International Journal of Molecular Sciences. 2018 volume 19, issue 8, page 2344.

Fluid dynamic characterization of a fluidized-bed perfusion bioreactor with CFD-DEM simulation. Huang, Z., Odeleye, A.O.O., Ye, H., Cui, Z. and Yang, A. J. Chem. Technol. Biotechnol. 2017 Volume 93, Issue 8, Pages 2316-2330.

Transcriptomics of human multipotent mesenchymal stromal cells: Retrospective analysis and future prospects. Kasoju, N., Wang, H., Zhang, B., George, J., Gao, S., Triffitt, J. T., Cui Z. & Ye, H. Biotechnology Advances. 2017 35: 407-418.

Preparation and characterization of cardamom extract-loaded gelatin nanoparticles as effective targeted drug delivery system to treat gliolastoma. H Nejat, M Rabiee, R Vaeshochian, M Tahriri, HE Jazayeri, J Rajadas, H Ye, Z Cui, L Tayebi. Reactive and Functional Polymers DOI: 10.1016/j.reactfunctpolym.2017.09.008.

Wan X, Li Z, Ye H, Cui Z. Three-dimensional perfused tumour spheroid model for anti-cancer drug screening. Biotechnol Lett. 2016 Aug;38(8):1389-95. doi: 10.1007/s10529-016-2035-1. PubMed PMID: 27167883; PubMed Central PMCID: PMC4942491.

Wu Y, Sun J, George J, Ye H, Cui Z, Li Z, Liu Q, Zhang Y, Ge D, Liu Y. Study of neuroprotective function of Ginkgo biloba extract (EGb761) derived-flavonoid monomers using a three-dimensional stem cell-derived neural model. Biotechnol Prog. 2016 May;32(3):735-44. doi: 10.1002/btpr.2255. PubMed PMID: 26919031.

Bianchi, F., Hofmann, F., Smith, A.J., Thompson, M.S., Probing multi-scale mechanical damage in connective tissues using x-ray diffraction, Acta Biomaterialia (2016), doi:

Zhang J., Cui Z., Field R., Moloney M.G., Rimmer S., Ye H. Thermo-responsive microcarriers based on poly(N-isopropylacrylamide). European Polymer Journal. 2015 June; 67:346-364. d.o.i: 10.1016/j.eurpolymj.2015.04.013.

Mouthuy PA, Groszkowski L, Ye H. Performances of a portable electrospinning apparatus. Biotechnol Lett. 2015 May;37(5):1107-16. doi: 10.1007/s10529-014-1760-6. Epub 2015 Jan 1.

Guan S., Xu J., Guo Y., Ge D., Liu T., Ma X., Cui Z. Pyrroloquinoline quinone against glutamate-induced neurotoxicity in cultured neural stem and progenitor cells. International Journal of Developmental Neuroscience. 2015 May; 42:37-45. d.o.i: 10.1016/j.ijdevneu.2015.02.008. PMID: 25702528

Li Z, Cui Z. Three-dimensional perfused cell culture. Biotechnology Advances. 2014; 32(2):243-254. d.o.i: 10.1016/j.biotechadv.2013.10.006.

Xia Xu, Yang Liu, Zhan Feng Cui. Effects of cryopreservation on human mesenchymal stem cells attached to different substrates. Journal of tissue engineering and regenerative medicine. 2014 Aug; 8(8):664-72. d.o.i: 10.1002/term.1570. PMID: 25066447

Reema Chawla, Aaron Tan, Maqsood Ahmed, Claire Crowley, Naiem S. Moiemen, Zhanfeng Cui, Peter E. Butler, Alexander M. Seifalian, A polyhedral oligomeric silsesquioxane–based bilayered dermal scaffold seeded with adipose tissue–derived stem cells: in vitro assessment of biomechanical properties, Journal of Surgical Research, Available online 9 January 2014, ISSN 0022-4804,

Gundogan B, Tan A, Farhatnia Y, Alavijeh MS, Cui Z, Seifalian AM. Bioabsorbable Stent Quo Vadis: A Case for Nano-Theranostics.  Theranostics. 2014 Feb 22;4(5):514-533. eCollection 2014. Review. PMID: 24672583

Zhaohui Li, Zhanfeng Cui, Three-dimensional perfused cell culture, Biotechnology Advances, Available online 29 October 2013, ISSN 0734-9750, (

Zhu H, Liu J, Qu J, Gao X, Pan T, Cui Z, Zhao X, Lu JR. Stress fermentation strategies for the production of hyperthermostable superoxide dismutase from Thermus thermophilus HB27: effects of ions. Extremophiles. 2013 Nov;17(6):995-1002. doi: 10.1007/s00792-013-0581-1. Epub 2013 Sep 13. PMID: 24030482 [PubMed - in process]

Li Z, Sun H, Zhang J, Zhang H, Meng F, Cui Z.  Development of in vitro 3D TissueFlex® islet model for diabetic drug efficacy testing.   PLoS One. 2013 Aug 15;8(8):e72612. doi: 10.1371/journal.pone.0072612.

Xuebin Ke, Yiming Huang, Tim R. Dargaville, Yiqun Fan, Zhanfeng Cui, Huaiyong Zhu, Modified alumina nanofiber membranes for protein separation, Separation and Purification Technology, Volume 120, 13 December 2013, Pages 239-244, ISSN 1383-5866, (

Jianguo Liu, Changzhen Chen, Baosheng Ge, Jianren Lu, Zhanfeng Cui, A novel membrane based process to isolate recombinant human chemokine receptor CCR3 produced in Escherichia coli, Journal of Membrane Science, Volumes 425–426, 1 January 2013, Pages 98-104, ISSN 0376-7388, (

Zhanfeng Cui, Kyongbum Lee, Biological engineering, Current Opinion in Chemical Engineering, Volume 2, Issue 1, February 2013, Pages 1-2, ISSN 2211-3398, (

Kaul H, Cui Z, Ventikos Y. A multi-paradigm modeling framework to simulate
dynamic reciprocity in a bioreactor. PLoS One. 2013;8(3):e59671. doi:
10.1371/journal.pone.0059671. Epub 2013 Mar 29. PubMed PMID: 23555740; PubMed
Central PMCID: PMC3612085.

Cui Z. 4th Annual predictive toxicology summit 2012. Expert Opin Drug Metab
Toxicol. 2013 Aug;9(8):1061-6. doi: 10.1517/17425255.2013.802306. Epub 2013 May 25.

Mouthuy, P., El-Sherbini, Y., Cui, Z., Ye, H. Layering PLGA-based electrospun membranes and cell sheets for engineering cartilage-bone transition. J Tissue Eng Regen M, 2013 Jun 11. doi: 10.1002/term.1765. [Epub ahead of print]

Mouthuy, P., Crossley, A., Ye, H Fabrication of Calcium Phosphate Fibres through Electrospinning and Sintering of Hydroxyapatite Nanoparticles. Materials Letters, 106, 145-150, 2013

Liu, J., Song, L., Jiang, C., Liu, Y., Ye, H., Cui, Z. Electrophysiological properties and synaptic function of mesenchymal stem cells during neurogenic differentiation - a mini-review. Inter J Artif Organs, 35(5), 323-37, 2012

Sambu, S., Xu, X., Ye, H., Cui, Z. Predicting the survival rate of mouse embryonic stem cells cryopreserved in alginate. P I Mech Eng H, 225, 1092-1107, 2011

Sambu, S., Schiffter, H.A., Cui, Z. Ye, H. RGDS-functionalized alginates improve the survival rate of encapsulated mouse embryonic stem cells during cryopreservation. Cryoletters, 32(5), 389-401, 2011

Lim, M., Panoskaltsis, N., Ye, H., Mantalaris, A. Optimization of in vitro erythropoiesis from CD34+ cord blood cells using design of experiments (DOE). Biochem Eng J, 55, 154-61, 2011

Sambu, S., Xu, X., Ye, H., Cui, Z. Overcoming Challenges in the Cryopreservation of Stem Cells in 3D Alginate Constructs. J Biotech, 150, S446-7, 2010

Mouthuy, P., Ye, H., Triffitt, J.T., Oommen, G., Cui, Z. Physico-chemical characterisation of functional electrospun scaffolds for bone and cartilage tissue engineering. P I Mech Eng H, 224 (H12), 1401-14, 2010

Zhu, Y., Liu, T., Ye, H., Song, K., Ma, X., Cui, Z. Enhancement of adipose-derived stem cell differentiation in scaffolds with IGF-I gene impregnation under dynamic microenvironment. Stem Cells Dev, 19, 1548-56, 2010

Yue, X., Drakakis, E., Lim, M., Radomska, A., Ye, H., Mantalaris, A., Panoskaltsis, N., Cass, A. A real-time, multi-channel monitoring system for stem cell culture process. IEEE Trans Biomed Circuits Syst, 2, 66-77, 2008

Radomska, A., Singhal, S., Ye, H., Lim, M., Mantalaris, A., Yue, X., Drakakis, E., Toumazou, C., Cass, A. Biocompatible ion selective electrode for monitoring metabolic activity during the growth and cultivation of human cells. Biosens Bioelectron, 24, 435-441, 2008

Lim, M., Ye, H., Drakakis, E., Yue, X., Cass, A., Panoskaltsis, N., Mantalaris, A. Towards information-rich bioprocessing: generation of spatio-temporal profiles through the use of design of experiments to determine optimal number and location of sensors - an example in thermal profiles. Biochem Eng J, 40, 1-7, 2008

Lim, M., Ye, H., Placzek, M., Mantalaris, A. Stem cell bioprocessing: Manufacturing cells for clinical applications. Bioworld Europe, S1, 10-13, 2007

Lim, M., Ye, H., Panoskaltsis, N., Drakakis, E., Yue, X., Cass, A., Radomska, A., Mantalaris, A. Intelligent bioprocessing for haematopoietic cell cultures using monitoring and design of experiments. Biotech Adv, 25, 353-368, 2007

Ye, H., Xia, Z., Ferguson D. J. P., Triffitt, J. T., Cui, Z. Studies on the use of hollow fibre membrane bioreactors for tissue generation by using rat bone marrow fibroblastic cells and a composite scaffold. J Mater Sci Mater Med, 18, 641-648, 2007

 Abdullah, N. S., Das, D. B., Ye, H., Cui, Z. 3D bone tissue growth in hollow fibre membrane bioreactor: implications of various process parameters on tissue nutrition. Inl J Artif Organs, 29, 841-51, 2006

Ye, H., Das, D. B., Cui, Z., Triffitt, J. T. Modelling nutrient transport in hollow fibre membrane bioreactor for growing dense bone tissue. J Membrane Sci, 272, 169-178, 2006

Xia, Z., Ye, H., Locklin, R. M., Ferguson, D. J., Cui, Z., Triffitt, J. T. Efficient characterization of human cell-bioceramic interactions in vitro and in vivo by using enhanced GFP-labelled mesenchymal stem cells. Biomaterials 26, 5790-5800, 2005

Xia, Z., Ye, H., Choong, C., Ferguson, D. J., Platt, N., Cui, Z. Triffitt, J. T. Macrophagic response to human mesenchymal stem cell and poly(epsilon-caprolactone) implantation in nonobese diabetic/severe combined immunodeficient mice. J Biomed Mater Res 71A, 538-548, 2004


  • Julian F Dye. From Secondary Intent to Accelerated Regenerative Healing: Emergence of the Bio-intelligent Scaffold Vasculogenic Strategy for Skin Reconstruction. Tissue Engineering and Regeneration: Vascularization for Tissue Engineering and Regenerative Medicine (eds Wolfgang Holnthoner, H. Redl, Andrea Banfi & James Kirkpatrick). Springer. 2018
  • Julian H. George, Sharlayne T. Waller, Hua Ye. 4.13 Use and Manipulation of Microporous Membranes in Mammalian Cell Cultures. Comprehensive Membrane Science and and Engineering, second edition. (eds Drioli, E., Giorno, L., and Fontananova, E.) Elsevier, 2017
  • Mouthuy, P, Ye, H. Biomaterials: electrospinning. Comprehensive Biotechnology, 2nd Ed, Vol 5 Murray, M., Ed, 23-36, Elsevier 2011
  • Zhou, S., Ye, H., Cui, Z. Complexity in modeling of cartilage tissue engineering. Comprehensive Biotechnology, 2nd Ed, Vol 5, Murray, M., Ed, 311-319, Elsevier, 2011
  • Ye, H., Cui, Z., Ellis, M. J., Chaudhuri, J. B., Macedo, H., Mantalaris, A. Hollow fibre membrane bioreactor technology for tissue engineering and stem cell therapy. Comprehensive Membrane Science and Technology. Vol 3, Drioli, E. , Giorno, L. Eds. Elsevier, 2010
  • Lim, M., Ye, H., Panoskaltsis, N., Mantalaris, A. Optimal expansion and differentiation of cord blood stem cells using design of experiments. Handbook of Cardiac Stem Cell Therapy. Dimarakis, I., Menasche, P., Habib, N. A., Gordon, M. Y. Eds. 265-282, Imperial College Press, London. 2009



  • Sambu, S., Cui, Z. Ye, H., A method for cryopreserving human embryonic stem cells (hESC) without using apoptosis inhibitors, GB1110331.4 Applicant: ISIS Innovation Ltd   (2011)
  • Cui, Z., Triffitt, J. T., Xia, Z., Ye, H. "Method and structure for growing living organic tissue", EP1425379B1,       Applicant: ISIS Innovation Ltd   (2006)