Flora Kennedy McConnell
St John's College
CDT Postgraduate Studentship in Healthcare Innovation (RCUK Digital Economy Programme grant number EP/G036861/1)
Quantifying collateral flow pathways in the brain
Your brain needs blood all the time to continue functioning. Even a short interruption can lead to fainting and a longer term blockage can result in a stroke, which kills brain tissue and often causes serious disability. Blood flows through a number of different routes to the brain and even when one is blocked it can get round another way (what we call collateral flow). However, this is not always very robust and can sometimes go wrong. What we would like to do is to measure how well blood is travelling around the brain, which pathways the blood is travelling through and see whether this information can help to identify which stroke patients are likely to be most at risk of a secondary stroke. We have a way of doing this at the moment, but we need to make it more accurate. To do this we will construct a mathematical model of blood flow and the measurement technique that will enable doctors to get more useful and trustworthy information.